Cunningham CN - Search Results

1

Hydrogel-Encapsulated Beads Enable Proximity-Driven Encoded Library Synthesis and Screening.

Cavett V, Chan AI, Cunningham CN, Paegel BM. Cavett V, et al. Among authors: cunningham cn. ACS Cent Sci. 2023 Jul 13;9(8):1603-1610. doi: 10.1021/acscentsci.3c00316. eCollection 2023 Aug 23. ACS Cent Sci. 2023. PMID: 37637732 Free PMC article.

2

Evaluating Translational Efficiency of Noncanonical Amino Acids to Inform the Design of Druglike Peptide Libraries.

Chan AI, Sawant MS, Burdick DJ, Tom J, Song A, Cunningham CN. Chan AI, et al. Among authors: cunningham cn. ACS Chem Biol. 2023 Jan 20;18(1):81-90. doi: 10.1021/acschembio.2c00712. Epub 2023 Jan 6. ACS Chem Biol. 2023. PMID: 36607609 Free PMC article.

3

Liposomal Permeation Assay for Droplet-Scale Pharmacokinetic Screening.

Hu J, Chan AI, Adaligil E, Kekessie I, Takahashi M, Song A, Cunningham CN, Paegel BM. Hu J, et al. Among authors: cunningham cn. J Med Chem. 2023 May 11;66(9):6288-6296. doi: 10.1021/acs.jmedchem.3c00138. Epub 2023 Apr 19. J Med Chem. 2023. PMID: 37075027 Free PMC article.

4

Ribosomal Synthesis of Macrocyclic Peptides with β²- and β^2,3-Homo-Amino Acids for the Development of Natural Product-Like Combinatorial Libraries.

Adaligil E, Song A, Hallenbeck KK, Cunningham CN, Fairbrother WJ. Adaligil E, et al. Among authors: cunningham cn. ACS Chem Biol. 2021 Jun 18;16(6):1011-1018. doi: 10.1021/acschembio.1c00062. Epub 2021 May 19. ACS Chem Biol. 2021. PMID: 34008946

5

Identification of Macrocyclic Peptide Families from Combinatorial Libraries Containing Noncanonical Amino Acids Using Cheminformatics and Bioinformatics Inspired Clustering.

Lee ML, Farag S, Del Cid JS, Bashore C, Hallenbeck KK, Gobbi A, Cunningham CN. Lee ML, et al. Among authors: cunningham cn. ACS Chem Biol. 2023 Jun 16;18(6):1425-1434. doi: 10.1021/acschembio.3c00159. Epub 2023 May 23. ACS Chem Biol. 2023. PMID: 37220419 Free PMC article.

6

Membrane Permeability in a Large Macrocyclic Peptide Driven by a Saddle-Shaped Conformation.

Faris JH, Adaligil E, Popovych N, Ono S, Takahashi M, Nguyen H, Plise E, Taechalertpaisarn J, Lee HW, Koehler MFT, Cunningham CN, Lokey RS. Faris JH, et al. Among authors: cunningham cn. J Am Chem Soc. 2024 Feb 21;146(7):4582-4591. doi: 10.1021/jacs.3c10949. Epub 2024 Feb 8. J Am Chem Soc. 2024. PMID: 38330910 Free PMC article.

7

Ribosomal Synthesis of Macrocyclic Peptides with Linear γ⁴- and β-Hydroxy-γ⁴-amino Acids.

Adaligil E, Song A, Cunningham CN, Fairbrother WJ. Adaligil E, et al. Among authors: cunningham cn. ACS Chem Biol. 2021 Aug 20;16(8):1325-1331. doi: 10.1021/acschembio.1c00292. Epub 2021 Jul 16. ACS Chem Biol. 2021. PMID: 34270222

8

Computational Site Saturation Mutagenesis of Canonical and Non-Canonical Amino Acids to Probe Protein-Peptide Interactions.

Holden JK, Pavlovicz R, Gobbi A, Song Y, Cunningham CN. Holden JK, et al. Among authors: cunningham cn. Front Mol Biosci. 2022 Apr 14;9:848689. doi: 10.3389/fmolb.2022.848689. eCollection 2022. Front Mol Biosci. 2022. PMID: 35495632 Free PMC article.

9

An Integrated Strategy for Assessing the Metabolic Stability and Biotransformation of Macrocyclic Peptides in Drug Discovery toward Oral Delivery.

Guo Y, Ji S, Wang W, Wong S, Yen CW, Hu C, Leung DH, Plise E, Zhang S, Zhang C, Anene UA, Zhang D, Cunningham CN, Khojasteh SC, Su D. Guo Y, et al. Among authors: cunningham cn. Anal Chem. 2022 Feb 1;94(4):2032-2041. doi: 10.1021/acs.analchem.1c04008. Epub 2022 Jan 18. Anal Chem. 2022. PMID: 35041378

10

Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling.

Phillips AH, Zhang Y, Cunningham CN, Zhou L, Forrest WF, Liu PS, Steffek M, Lee J, Tam C, Helgason E, Murray JM, Kirkpatrick DS, Fairbrother WJ, Corn JE. Phillips AH, et al. Among authors: cunningham cn. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11379-84. doi: 10.1073/pnas.1302407110. Epub 2013 Jun 25. Proc Natl Acad Sci U S A. 2013. PMID: 23801757 Free PMC article.

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