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Targeted delivery of a PD-1-blocking scFv by CD133-specific CAR-T cells using nonviral Sleeping Beauty transposition shows enhanced antitumour efficacy for advanced hepatocellular carcinoma.
Yang C, You J, Pan Q, Tang Y, Cai L, Huang Y, Gu J, Wang Y, Yang X, Du Y, Ouyang D, Chen H, Zhong H, Li Y, Yang J, Han Y, Sun F, Chen Y, Wang Q, Weng D, Liu Z, Xiang T, Xia J. Yang C, et al. Among authors: chen h, chen y. BMC Med. 2023 Aug 28;21(1):327. doi: 10.1186/s12916-023-03016-0. BMC Med. 2023. PMID: 37635247 Free PMC article.
BMP9-induced vascular normalisation improves the efficacy of immunotherapy against hepatitis B virus-associated hepatocellular carcinoma.
Han Y, Pan Q, Guo Z, Du Y, Zhang Y, Liu Y, Zhao J, Xu J, Yang J, Ouyang D, Tang Y, Wang Q, Li Y, He J, Yang M, Chen H, Yang C, Yang X, You J, Chen Y, Ren M, Zhu Y, Xia J, Xiang T. Han Y, et al. Among authors: chen h, chen y. Clin Transl Med. 2023 May;13(5):e1247. doi: 10.1002/ctm2.1247. Clin Transl Med. 2023. PMID: 37132170 Free PMC article.
Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia.
Tang Y, Wu J, Sun X, Tan S, Li W, Yin S, Liu L, Chen Y, Liu Y, Tan Q, Jiang Y, Yang W, Huang W, Weng C, Wu Q, Lu Y, Yuan H, Xiao Q, Chen AF, Xu Q, Billiar TR, Cai J. Tang Y, et al. Among authors: chen af, chen y. Cell Rep. 2024 May 15;43(5):114237. doi: 10.1016/j.celrep.2024.114237. Online ahead of print. Cell Rep. 2024. PMID: 38753484 Free article.
Metabolic biomarkers significantly enhance the prediction of HBV-related ACLF occurrence and outcomes.
Zhang Y, Tan W, Wang X, Zheng X, Huang Y, Li B, Meng Z, Gao Y, Qian Z, Liu F, Lu X, Shi Y, Shang J, Yan H, Zheng Y, Zhang W, Gu W, Qiao L, Deng G, Zhou Y, Hou Y, Zhang Q, Xiong S, Liu J, Duan L, Chen R, Chen J, Jiang X, Luo S, Chen Y, Jiang C, Zhao J, Ji L, Mei X, Li J, Li T, Zheng R, Zhou X, Ren H, Cheng X, Guo L, Li H; Chinese (Acute on) Chronic Liver Failure Consortium (Ch-CLIF.C). Zhang Y, et al. Among authors: chen j, chen r, chen y. J Hepatol. 2023 Nov;79(5):1159-1171. doi: 10.1016/j.jhep.2023.07.011. Epub 2023 Jul 29. J Hepatol. 2023. PMID: 37517452
Prognosis prediction performs better in patients with non-cirrhosis hepatitis B virus-related acute-on-chronic liver failure than those with cirrhosis.
Yu X, Li H, Tan W, Wang X, Zheng X, Huang Y, Li B, Meng Z, Gao Y, Qian Z, Liu F, Lu X, Shang J, Yan H, Zheng Y, Zhang W, Yin S, Gu W, Deng G, Xiang X, Zhou Y, Hou Y, Zhang Q, Xiong S, Liu J, Chen R, Long L, Chen J, Jiang X, Luo S, Chen Y, Jiang C, Zhao J, Ji L, Mei X, Li J, Li T, Zheng R, Zhou X, Ren H, Sheng J, Shi Y. Yu X, et al. Among authors: chen j, chen r, chen y. Front Microbiol. 2022 Dec 9;13:1013439. doi: 10.3389/fmicb.2022.1013439. eCollection 2022. Front Microbiol. 2022. PMID: 36569093 Free PMC article.
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