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Inhibition of MALT1 paracaspase activity improves lesion recovery following spinal cord injury.
Zhang H, Sun G, Li X, Fu Z, Guo C, Cao G, Wang B, Wang Q, Yang S, Li D, Xia X, Li P, Zhu J, Zhou W, Zheng L, Li J, Zhang L, Hao J, Zhou L, Bornancin F, Li Z, Yin Z, Gao Y. Zhang H, et al. Among authors: bornancin f. Sci Bull (Beijing). 2019 Aug 30;64(16):1179-1194. doi: 10.1016/j.scib.2019.04.026. Epub 2019 Apr 22. Sci Bull (Beijing). 2019. PMID: 36659689
A phospho-harmonic orchestra plays the NLRP3 score.
Bornancin F, Dekker C. Bornancin F, et al. Front Immunol. 2023 Nov 3;14:1281607. doi: 10.3389/fimmu.2023.1281607. eCollection 2023. Front Immunol. 2023. PMID: 38022631 Free PMC article. Review.
Ligandability Assessment of IL-1β by Integrated Hit Identification Approaches.
Vulpetti A, Rondeau JM, Bellance MH, Blank J, Boesch R, Boettcher A, Bornancin F, Buhr S, Connor LE, Dumelin CE, Esser O, Hediger M, Hintermann S, Hommel U, Koch E, Lapointe G, Leder L, Lehmann S, Lehr P, Meier P, Muller L, Ostermeier D, Ramage P, Schiebel-Haddad S, Smith AB, Stojanovic A, Velcicky J, Yamamoto R, Hurth K. Vulpetti A, et al. Among authors: bornancin f. J Med Chem. 2024 May 23;67(10):8141-8160. doi: 10.1021/acs.jmedchem.4c00240. Epub 2024 May 10. J Med Chem. 2024. PMID: 38728572
Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1β.
Hommel U, Hurth K, Rondeau JM, Vulpetti A, Ostermeier D, Boettcher A, Brady JP, Hediger M, Lehmann S, Koch E, Blechschmidt A, Yamamoto R, Tundo Dottorello V, Haenni-Holzinger S, Kaiser C, Lehr P, Lingel A, Mureddu L, Schleberger C, Blank J, Ramage P, Freuler F, Eder J, Bornancin F. Hommel U, et al. Among authors: bornancin f. Nat Commun. 2023 Sep 7;14(1):5497. doi: 10.1038/s41467-023-41190-0. Nat Commun. 2023. PMID: 37679328 Free PMC article.
MALT1 Is a Targetable Driver of Epithelial-to-Mesenchymal Transition in Claudin-Low, Triple-Negative Breast Cancer.
Lee JL, Ekambaram P, Carleton NM, Hu D, Klei LR, Cai Z, Myers MI, Hubel NE, Covic L, Agnihotri S, Krappmann D, Bornancin F, Lee AV, Oesterreich S, McAllister-Lucas LM, Lucas PC. Lee JL, et al. Among authors: bornancin f. Mol Cancer Res. 2022 Mar 1;20(3):373-386. doi: 10.1158/1541-7786.MCR-21-0208. Mol Cancer Res. 2022. PMID: 34753803 Free PMC article.
75 results