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Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies.
Hong L, Braden DC, Zhao Y, Skoko JJ, Chang F, Woodcock SR, Uvalle C, Casey A, Wood K, Salvatore SR, Asan A, Harkness T, Fagunloye A, Razzaghi M, Straub A, Spies M, Brown DD, Lee AV, Schopfer F, Freeman BA, Neumann CA. Hong L, et al. Among authors: freeman ba. Redox Biol. 2023 Oct;66:102856. doi: 10.1016/j.redox.2023.102856. Epub 2023 Aug 19. Redox Biol. 2023. PMID: 37633047 Free PMC article.
Fatty acid transduction of nitric oxide signaling: multiple nitrated unsaturated fatty acid derivatives exist in human blood and urine and serve as endogenous peroxisome proliferator-activated receptor ligands.
Baker PR, Lin Y, Schopfer FJ, Woodcock SR, Groeger AL, Batthyany C, Sweeney S, Long MH, Iles KE, Baker LM, Branchaud BP, Chen YE, Freeman BA. Baker PR, et al. Among authors: freeman ba. J Biol Chem. 2005 Dec 23;280(51):42464-75. doi: 10.1074/jbc.M504212200. Epub 2005 Oct 14. J Biol Chem. 2005. PMID: 16227625 Free PMC article.
Nitro-fatty acid formation and signaling.
Freeman BA, Baker PR, Schopfer FJ, Woodcock SR, Napolitano A, d'Ischia M. Freeman BA, et al. J Biol Chem. 2008 Jun 6;283(23):15515-9. doi: 10.1074/jbc.R800004200. Epub 2008 Feb 19. J Biol Chem. 2008. PMID: 18285326 Free PMC article. Review. No abstract available.
Nitro-oleic acid, a novel and irreversible inhibitor of xanthine oxidoreductase.
Kelley EE, Batthyany CI, Hundley NJ, Woodcock SR, Bonacci G, Del Rio JM, Schopfer FJ, Lancaster JR Jr, Freeman BA, Tarpey MM. Kelley EE, et al. Among authors: freeman ba. J Biol Chem. 2008 Dec 26;283(52):36176-84. doi: 10.1074/jbc.M802402200. Epub 2008 Oct 29. J Biol Chem. 2008. PMID: 18974051 Free PMC article.
338 results