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Adipocyte HSL is required for maintaining circulating vitamin A and RBP4 levels during fasting.
Steinhoff JS, Wagner C, Dähnhardt HE, Košić K, Meng Y, Taschler U, Pajed L, Yang N, Wulff S, Kiefer MF, Petricek KM, Flores RE, Li C, Dittrich S, Sommerfeld M, Guillou H, Henze A, Raila J, Wowro SJ, Schoiswohl G, Lass A, Schupp M. Steinhoff JS, et al. Among authors: pajed l. EMBO Rep. 2024 May 20. doi: 10.1038/s44319-024-00158-x. Online ahead of print. EMBO Rep. 2024. PMID: 38769419 Free article.
Carboxylesterase 2a deletion provokes hepatic steatosis and insulin resistance in mice involving impaired diacylglycerol and lysophosphatidylcholine catabolism.
Chalhoub G, Jamnik A, Pajed L, Kolleritsch S, Hois V, Bagaric A, Prem D, Tilp A, Kolb D, Wolinski H, Taschler U, Züllig T, Rechberger GN, Fuchs C, Trauner M, Schoiswohl G, Haemmerle G. Chalhoub G, et al. Among authors: pajed l. Mol Metab. 2023 Jun;72:101725. doi: 10.1016/j.molmet.2023.101725. Epub 2023 Apr 12. Mol Metab. 2023. PMID: 37059417 Free PMC article.
Interleukin-6 initiates muscle- and adipose tissue wasting in a novel C57BL/6 model of cancer-associated cachexia.
Pototschnig I, Feiler U, Diwoky C, Vesely PW, Rauchenwald T, Paar M, Bakiri L, Pajed L, Hofer P, Kashofer K, Sukhbaatar N, Schoiswohl G, Weichhart T, Hoefler G, Bock C, Pichler M, Wagner EF, Zechner R, Schweiger M. Pototschnig I, et al. Among authors: pajed l. J Cachexia Sarcopenia Muscle. 2023 Feb;14(1):93-107. doi: 10.1002/jcsm.13109. Epub 2022 Nov 9. J Cachexia Sarcopenia Muscle. 2023. PMID: 36351437 Free PMC article.
Rosiglitazone Reverses Inflammation in Epididymal White Adipose Tissue in Hormone-Sensitive Lipase-Knockout Mice.
Kotzbeck P, Taschler U, Haudum C, Foessl I, Schoiswohl G, Boulgaropoulos B, Bounab K, Einsiedler J, Pajed L, Tilp A, Schwarz A, Eichmann TO, Obermayer-Pietsch B, Giordano A, Cinti S, Zechner R, Pieber TR. Kotzbeck P, et al. Among authors: pajed l. J Lipid Res. 2023 Jan;64(1):100305. doi: 10.1016/j.jlr.2022.100305. Epub 2022 Oct 20. J Lipid Res. 2023. PMID: 36273647 Free PMC article.
Advanced lipodystrophy reverses fatty liver in mice lacking adipocyte hormone-sensitive lipase.
Pajed L, Taschler U, Tilp A, Hofer P, Kotzbeck P, Kolleritsch S, Radner FPW, Pototschnig I, Wagner C, Schratter M, Eder S, Huetter S, Schreiber R, Haemmerle G, Eichmann TO, Schweiger M, Hoefler G, Kershaw EE, Lass A, Schoiswohl G. Pajed L, et al. Commun Biol. 2021 Mar 10;4(1):323. doi: 10.1038/s42003-021-01858-z. Commun Biol. 2021. PMID: 33692445 Free PMC article.
Lysosomal acid lipase is the major acid retinyl ester hydrolase in cultured human hepatic stellate cells but not essential for retinyl ester degradation.
Wagner C, Hois V, Pajed L, Pusch LM, Wolinski H, Trauner M, Zimmermann R, Taschler U, Lass A. Wagner C, et al. Among authors: pajed l. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Aug;1865(8):158730. doi: 10.1016/j.bbalip.2020.158730. Epub 2020 May 1. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32361002 Free PMC article.
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