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Exploiting the CD200-CD200R immune checkpoint axis in multiple myeloma to enhance CAR T-cell therapy.
Tang Y, Liu W, Kadu S, Johnson O, Hasanali ZS, Kelly A, Shestov A, Pajarillo R, Greenblatt E, Holmes M, Wang LP, Shih N, O'Connor RS, Ruella M, Garfall AL, Allman D, Vogl DT, Cohen A, June CH, Sheppard NC. Tang Y, et al. Among authors: allman d. Blood. 2024 Jan 11;143(2):139-151. doi: 10.1182/blood.2022018658. Blood. 2024. PMID: 37616575 Free PMC article.
Expression of the transcription factor Klf6 by thymic epithelial cells is required for thymus development.
Malin J, Martinez-Ruiz GU, Zhao Y, Shissler SC, Cowan JE, Ding Y, Morales-Sanchez A, Ishikawa M, Lavaert M, Das A, Butcher D, Warner AC, Kallarakal M, Chen J, Kedei N, Kelly M, Brinster LR, Allman D, Bhandoola A. Malin J, et al. Among authors: allman d. Sci Adv. 2023 Nov 17;9(46):eadg8126. doi: 10.1126/sciadv.adg8126. Epub 2023 Nov 15. Sci Adv. 2023. PMID: 37967174 Free PMC article.
Increased activity of IRE1 improves the clinical presentation of EAE.
Bracchi-Ricard V, Nguyen K, Ricci D, Gaudette B, Henao-Mejia J, Brambilla R, Martynyuk T, Gidalevitz T, Allman D, Bethea JR, Argon Y. Bracchi-Ricard V, et al. Among authors: allman d. FASEB J. 2023 Dec;37(12):e23283. doi: 10.1096/fj.202300769RR. FASEB J. 2023. PMID: 37983957
Human IL-6 fosters long-term engraftment of patient-derived disease-driving myeloma cells in immunodeficient mice.
Hasanali ZS, Garfall AL, Burzenski L, Shultz LD, Tang Y, Kadu S, Sheppard NC, Liu W, Dopkin D, Vogl DT, Cohen AD, Waxman AJ, Susanibar-Adaniya SP, Carroll M, Stadtmauer EA, Allman D. Hasanali ZS, et al. Among authors: allman d. JCI Insight. 2024 May 7;9(10):e177300. doi: 10.1172/jci.insight.177300. JCI Insight. 2024. PMID: 38713510 Free article.
Unusual lineage plasticity revealed by YY1 knockout in pro-B cells.
Banerjee S, Sanyal S, Hodawadekar S, Naiyer S, Bano N, Banerjee A, Rhoades J, Dong D, Allman D, Atchison ML. Banerjee S, et al. Among authors: allman d. bioRxiv [Preprint]. 2024 Mar 27:2024.03.22.586298. doi: 10.1101/2024.03.22.586298. bioRxiv. 2024. PMID: 38586061 Free PMC article. Preprint.
Bone marrow plasma cells require P2RX4 to sense extracellular ATP.
Ishikawa M, Hasanali ZS, Zhao Y, Das A, Lavaert M, Roman CJ, Londregan J, Allman D, Bhandoola A. Ishikawa M, et al. Among authors: allman d. Nature. 2024 Feb;626(8001):1102-1107. doi: 10.1038/s41586-024-07047-2. Epub 2024 Feb 14. Nature. 2024. PMID: 38355795 Free PMC article.
Human IL-6 fosters long-term engraftment of patient derived disease-driving myeloma cells in immunodeficient mice.
Hasanali ZS, Garfall AL, Burzenski L, Shultz LD, Tang Y, Kadu S, Sheppard NC, Dopkin D, Vogl DT, Cohen AD, Waxman AJ, Susanibar-Adaniya SP, Carroll M, Stadtmauer EA, Allman D. Hasanali ZS, et al. Among authors: allman d. bioRxiv [Preprint]. 2024 Jan 24:2024.01.21.576547. doi: 10.1101/2024.01.21.576547. bioRxiv. 2024. PMID: 38328086 Free PMC article. Updated. Preprint.
Immunotherapy targeting B cells and long-lived plasma cells effectively eliminates pre-existing donor-specific allo-antibodies.
Zhang Z, Markmann C, Yu M, Agarwal D, Rostami S, Wang W, Liu C, Zhao H, Ochoa T, Parvathaneni K, Xu X, Li E, Gonzalez V, Khadka R, Hoffmann J, Knox JJ, Scholler J, Marcellus B, Allman D, Fraietta JA, Samelson-Jones B, Milone MC, Monos D, Garfall AL, Naji A, Bhoj VG. Zhang Z, et al. Among authors: allman d. Cell Rep Med. 2023 Dec 19;4(12):101336. doi: 10.1016/j.xcrm.2023.101336. Cell Rep Med. 2023. PMID: 38118406 Free PMC article.
219 results