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A complement atlas identifies interleukin-6-dependent alternative pathway dysregulation as a key druggable feature of COVID-19.
Sci Transl Med. 2023 Aug 23;15(710):eadi0252. doi: 10.1126/scitranslmed.adi0252. Epub 2023 Aug 23.
Sci Transl Med. 2023.
PMID: 37611083
Targeting gliovascular connexins prevents inflammatory blood-brain barrier leakage and astrogliosis.
De Bock M, De Smet M, Verwaerde S, Tahiri H, Schumacher S, Van Haver V, Witschas K, Steinhäuser C, Rouach N, Vandenbroucke RE, Leybaert L.
De Bock M, et al. Among authors: verwaerde s.
JCI Insight. 2022 Aug 22;7(16):e135263. doi: 10.1172/jci.insight.135263.
JCI Insight. 2022.
PMID: 35881483
Free PMC article.
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Blocking connexin43 hemichannels protects mice against tumour necrosis factor-induced inflammatory shock.
Delvaeye T, De Smet MAJ, Verwaerde S, Decrock E, Czekaj A, Vandenbroucke RE, Lemeire K, Gonçalves A, Declercq W, Vandenabeele P, Krysko DV, Leybaert L.
Delvaeye T, et al. Among authors: verwaerde s.
Sci Rep. 2019 Nov 12;9(1):16623. doi: 10.1038/s41598-019-52900-4.
Sci Rep. 2019.
PMID: 31719598
Free PMC article.
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