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A complement atlas identifies interleukin-6-dependent alternative pathway dysregulation as a key druggable feature of COVID-19.
Van Damme KFA, Hoste L, Declercq J, De Leeuw E, Maes B, Martens L, Colman R, Browaeys R, Bosteels C, Verwaerde S, Vermeulen N, Lameire S, Debeuf N, Deckers J, Stordeur P, Depuydt P, Van Braeckel E, Vandekerckhove L, Guilliams M, Schetters STT, Haerynck F, Tavernier SJ, Lambrecht BN. Van Damme KFA, et al. Among authors: lambrecht bn. Sci Transl Med. 2023 Aug 23;15(710):eadi0252. doi: 10.1126/scitranslmed.adi0252. Epub 2023 Aug 23. Sci Transl Med. 2023. PMID: 37611083
Conventional and monocyte-derived CD11b(+) dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen.
Plantinga M, Guilliams M, Vanheerswynghels M, Deswarte K, Branco-Madeira F, Toussaint W, Vanhoutte L, Neyt K, Killeen N, Malissen B, Hammad H, Lambrecht BN. Plantinga M, et al. Among authors: lambrecht bn. Immunity. 2013 Feb 21;38(2):322-35. doi: 10.1016/j.immuni.2012.10.016. Epub 2013 Jan 24. Immunity. 2013. PMID: 23352232 Free article.
The mucosal adjuvant cholera toxin B instructs non-mucosal dendritic cells to promote IgA production via retinoic acid and TGF-β.
Gloudemans AK, Plantinga M, Guilliams M, Willart MA, Ozir-Fazalalikhan A, van der Ham A, Boon L, Harris NL, Hammad H, Hoogsteden HC, Yazdanbakhsh M, Hendriks RW, Lambrecht BN, Smits HH. Gloudemans AK, et al. Among authors: lambrecht bn. PLoS One. 2013;8(3):e59822. doi: 10.1371/journal.pone.0059822. Epub 2013 Mar 20. PLoS One. 2013. PMID: 23527272 Free PMC article.
The function of Fcγ receptors in dendritic cells and macrophages.
Guilliams M, Bruhns P, Saeys Y, Hammad H, Lambrecht BN. Guilliams M, et al. Among authors: lambrecht bn. Nat Rev Immunol. 2014 Feb;14(2):94-108. doi: 10.1038/nri3582. Epub 2014 Jan 21. Nat Rev Immunol. 2014. PMID: 24445665 Review.
420 results