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Multicomponent Synthesis of the SARS-CoV-2 Main Protease Inhibitor Nirmatrelvir.
J Org Chem. 2023 Sep 1;88(17):12565-12571. doi: 10.1021/acs.joc.3c01274. Epub 2023 Aug 22.
J Org Chem. 2023.
PMID: 37607396
Free PMC article.
Brønsted Acid-Catalyzed Cyanotritylation of Aldehydes by Trityl Isocyanide.
Cioc RC, Schuckman P, Preschel HD, Vlaar T, Ruijter E, Orru RV.
Cioc RC, et al. Among authors: preschel hd.
Org Lett. 2016 Aug 5;18(15):3562-5. doi: 10.1021/acs.orglett.6b01481. Epub 2016 Jul 12.
Org Lett. 2016.
PMID: 27404343
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Trityl Isocyanide as a Mechanistic Probe in Multicomponent Chemistry: Walking the Line between Ugi- and Strecker-type Reactions.
Cioc RC, Preschel HD, van der Heijden G, Ruijter E, Orru RV.
Cioc RC, et al. Among authors: preschel hd.
Chemistry. 2016 Jun 1;22(23):7837-42. doi: 10.1002/chem.201600285. Epub 2016 Apr 26.
Chemistry. 2016.
PMID: 27112103
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Iron-Catalysed Carbene Transfer to Isocyanides as a Platform for Heterocycle Synthesis.
Roose TR, Preschel HD, Mayo Tejedor H, Roozee JC, Hamlin TA, Maes BUW, Ruijter E, Orru RVA.
Roose TR, et al. Among authors: preschel hd.
Chemistry. 2023 Feb 10;29(9):e202203074. doi: 10.1002/chem.202203074. Epub 2022 Dec 20.
Chemistry. 2023.
PMID: 36305372
Free PMC article.
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