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Multicomponent Synthesis of the SARS-CoV-2 Main Protease Inhibitor Nirmatrelvir.
Preschel HD, Otte RT, Zhuo Y, Ruscoe RE, Burke AJ, Kellerhals R, Horst B, Hennig S, Janssen E, Green AP, Turner NJ, Ruijter E. Preschel HD, et al. Among authors: hennig s. J Org Chem. 2023 Sep 1;88(17):12565-12571. doi: 10.1021/acs.joc.3c01274. Epub 2023 Aug 22. J Org Chem. 2023. PMID: 37607396 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33453832
Fluorescent RNA tags: current and future applications.
Hennig S, Neubacher S. Hennig S, et al. Future Med Chem. 2019 Oct;11(19):2483-2485. doi: 10.4155/fmc-2019-0207. Future Med Chem. 2019. PMID: 31633397 Free article. No abstract available.
Discovery of N-(4-Aminobutyl)-N'-(2-methoxyethyl)guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine Dimethylaminohydrolase-1 (hDDAH-1).
Lunk I, Litty FA, Hennig S, Vetter IR, Kotthaus J, Altmann KS, Ott G, Havemeyer A, Carrillo García C, Clement B, Schade D. Lunk I, et al. Among authors: hennig s. J Med Chem. 2020 Jan 9;63(1):425-432. doi: 10.1021/acs.jmedchem.9b01230. Epub 2019 Dec 31. J Med Chem. 2020. PMID: 31841335
Vaccination with a bacterial peptide conjugated to SARS-CoV-2 receptor-binding domain accelerates immunity and protects against COVID-19.
Blanas A, Karsjens H, de Ligt A, Huijbers EJM, van Loon K, Denisov SS, Durukan C, Engbersen DJM, Groen J, Hennig S, Hackeng TM, van Beijnum JR, Griffioen AW. Blanas A, et al. Among authors: hennig s. iScience. 2022 Aug 19;25(8):104719. doi: 10.1016/j.isci.2022.104719. Epub 2022 Jul 5. iScience. 2022. PMID: 35813877 Free PMC article.
Structure-driven approaches and technologies for drug discovery.
Richters A, Hennig S. Richters A, et al. Among authors: hennig s. Drug Discov Today Technol. 2021 Dec;40:25-26. doi: 10.1016/j.ddtec.2021.11.001. Epub 2021 Nov 24. Drug Discov Today Technol. 2021. PMID: 34916016 No abstract available.
218 results