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Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers.
J Am Chem Soc. 2023 Aug 30;145(34):18760-18766. doi: 10.1021/jacs.3c07337. Epub 2023 Aug 22.
J Am Chem Soc. 2023.
PMID: 37606244
Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers.
Zhang D, Atochina-Vasserman EN, Maurya DS, Liu M, Xiao Q, Lu J, Lauri G, Ona N, Reagan EK, Ni H, Weissman D, Percec V.
Zhang D, et al. Among authors: reagan ek.
J Am Chem Soc. 2021 Nov 3;143(43):17975-17982. doi: 10.1021/jacs.1c09585. Epub 2021 Oct 21.
J Am Chem Soc. 2021.
PMID: 34672554
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The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity.
Zhang D, Atochina-Vasserman EN, Lu J, Maurya DS, Xiao Q, Liu M, Adamson J, Ona N, Reagan EK, Ni H, Weissman D, Percec V.
Zhang D, et al. Among authors: reagan ek.
J Am Chem Soc. 2022 Mar 23;144(11):4746-4753. doi: 10.1021/jacs.2c00273. Epub 2022 Mar 9.
J Am Chem Soc. 2022.
PMID: 35263098
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Modified E2 Glycoprotein of Hepatitis C Virus Enhances Proinflammatory Cytokines and Protective Immune Response.
Vijayamahantesh V, Patra T, Meyer K, Alameh MG, Reagan EK, Weissman D, Ray R.
Vijayamahantesh V, et al. Among authors: reagan ek.
J Virol. 2022 Jun 22;96(12):e0052322. doi: 10.1128/jvi.00523-22. Epub 2022 May 25.
J Virol. 2022.
PMID: 35612312
Free PMC article.
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Hepatitis C virus E1 and modified E2 delivered from an mRNA vaccine induces protective immunity.
Patra T, Meyer K, Haga Y, Reagan EK, Weissman D, Ray R.
Patra T, et al. Among authors: reagan ek.
NPJ Vaccines. 2023 Mar 18;8(1):42. doi: 10.1038/s41541-023-00635-9.
NPJ Vaccines. 2023.
PMID: 36934116
Free PMC article.
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Screening Libraries to Discover Molecular Design Principles for the Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers Derived from Plant Phenolic Acids.
Lu J, Atochina-Vasserman EN, Maurya DS, Shalihin MI, Zhang D, Chenna SS, Adamson J, Liu M, Shah HUR, Shah H, Xiao Q, Queeley B, Ona NA, Reagan EK, Ni H, Sahoo D, Peterca M, Weissman D, Percec V.
Lu J, et al. Among authors: reagan ek.
Pharmaceutics. 2023 May 23;15(6):1572. doi: 10.3390/pharmaceutics15061572.
Pharmaceutics. 2023.
PMID: 37376020
Free PMC article.
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Hepatitis C virus modified sE2F442NYT as an antigen in candidate vaccine facilitates human immune cell activation.
Haga Y, Meyer K, Sung MMH, Reagan EK, Weissman D, Ray R.
Haga Y, et al. Among authors: reagan ek.
J Virol. 2024 Jan 23;98(1):e0180923. doi: 10.1128/jvi.01809-23. Epub 2023 Dec 12.
J Virol. 2024.
PMID: 38084956
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