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Page 1
The effects of antibiotic use on the dynamics of the microbiome and resistome in pigs.
Tams KW, Larsen I, Hansen JE, Spiegelhauer H, Strøm-Hansen AD, Rasmussen S, Ingham AC, Kalmar L, Kean IRL, Angen Ø, Holmes MA, Pedersen K, Jelsbak L, Folkesson A, Larsen AR, Strube ML. Tams KW, et al. Among authors: kean irl. Anim Microbiome. 2023 Aug 21;5(1):39. doi: 10.1186/s42523-023-00258-4. Anim Microbiome. 2023. PMID: 37605221 Free PMC article.
Short-duration selective decontamination of the digestive tract infection control does not contribute to increased antimicrobial resistance burden in a pilot cluster randomised trial (the ARCTIC Study).
Kean IRL, Clark JA, Zhang Z, Daubney E, White D, Ferrando-Vivas P, Milla G, Cuthbertson B, Pappachan J, Klein N, Mouncey P, Rowan K, Myburgh J, Gouliouris T, Baker S, Parkhill J, Pathan N, Arctic Research Team. Kean IRL, et al. Gut. 2024 May 10;73(6):910-921. doi: 10.1136/gutjnl-2023-330851. Gut. 2024. PMID: 38253478 Free PMC article. Clinical Trial.
Enhanced CD95 and interleukin 18 signalling accompany T cell receptor Vβ21.3+ activation in multi-inflammatory syndrome in children.
Zhang Z, Kean IRL, Dratva LM, Clark JA, Syrimi E, Khan N, Daubney E, White D, O'Neill L, Chisholm C, Payne C, Benkenstein S, Kupiec K, Galassini R, Wright V, Winmill H, Robbins C, Brown K, Ramnarayan P, Scholefield B, Peters M, Klein N, Montgomery H, Meyer KB, Teichmann SA, Bryant C, Taylor G, Pathan N. Zhang Z, et al. Among authors: kean irl. Nat Commun. 2024 May 18;15(1):4227. doi: 10.1038/s41467-024-48699-y. Nat Commun. 2024. PMID: 38762592 Free PMC article.
The rapid detection of respiratory pathogens in critically ill children.
Clark JA, Conway Morris A, Curran MD, White D, Daubney E, Kean IRL, Navapurkar V, Bartholdson Scott J, Maes M, Bousfield R, Török ME, Inwald D, Zhang Z, Agrawal S, Kanaris C, Khokhar F, Gouliouris T, Baker S, Pathan N. Clark JA, et al. Among authors: kean irl. Crit Care. 2023 Jan 10;27(1):11. doi: 10.1186/s13054-023-04303-1. Crit Care. 2023. PMID: 36627688 Free PMC article.
Profiling gut microbiota and bile acid metabolism in critically ill children.
Kean IRL, Wagner J, Wijeyesekera A, De Goffau M, Thurston S, Clark JA, White DK, Ridout J, Agrawal S, Kayani R, O'Donnell R, Ramnarayan P, Peters MJ, Klein N, Holmes E, Parkhill J, Baker S, Pathan N. Kean IRL, et al. Sci Rep. 2022 Jun 21;12(1):10432. doi: 10.1038/s41598-022-13640-0. Sci Rep. 2022. PMID: 35729169 Free PMC article.
HAM-ART: An optimised culture-free Hi-C metagenomics pipeline for tracking antimicrobial resistance genes in complex microbial communities.
Kalmar L, Gupta S, Kean IRL, Ba X, Hadjirin N, Lay EM, de Vries SPW, Bateman M, Bartlet H, Hernandez-Garcia J, Tucker AW, Restif O, Stevens MP, Wood JLN, Maskell DJ, Grant AJ, Holmes MA. Kalmar L, et al. Among authors: kean irl. PLoS Genet. 2022 Mar 14;18(3):e1009776. doi: 10.1371/journal.pgen.1009776. eCollection 2022 Mar. PLoS Genet. 2022. PMID: 35286304 Free PMC article.
Rapid Assay for Sick Children with Acute Lung infection Study (RASCALS): diagnostic cohort study protocol.
Clark JA, Kean IRL, Curran MD, Khokhar F, White D, Daubney E, Conway Morris A, Navapurkar V, Bartholdson Scott J, Maes M, Bousfield R, Gouliouris T, Agrawal S, Inwald D, Zhang Z, Török ME, Baker S, Pathan N. Clark JA, et al. Among authors: kean irl. BMJ Open. 2021 Nov 29;11(11):e056197. doi: 10.1136/bmjopen-2021-056197. BMJ Open. 2021. PMID: 34845080 Free PMC article.
12 results