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Structure-Activity Relationship of Truncated 2,8-Disubstituted-Adenosine Derivatives as Dual A2A/A3 Adenosine Receptor Antagonists and Their Cancer Immunotherapeutic Activity.
Kim G, Hou X, Byun WS, Kim G, Jarhad DB, Lee G, Hyun YE, Yu J, Lee CS, Qu S, Warnick E, Gao ZG, Kim JY, Ji S, Shin H, Choi JR, Jacobson KA, Lee HW, Lee SK, Jeong LS. Kim G, et al. Among authors: lee g, lee sk, lee hw, lee cs. J Med Chem. 2023 Sep 14;66(17):12249-12265. doi: 10.1021/acs.jmedchem.3c00806. Epub 2023 Aug 21. J Med Chem. 2023. PMID: 37603705
Discovery of a new nucleoside template for human A3 adenosine receptor ligands: D-4'-thioadenosine derivatives without 4'-hydroxymethyl group as highly potent and selective antagonists.
Jeong LS, Choe SA, Gunaga P, Kim HO, Lee HW, Lee SK, Tosh DK, Patel A, Palaniappan KK, Gao ZG, Jacobson KA, Moon HR. Jeong LS, et al. Among authors: lee sk, lee hw. J Med Chem. 2007 Jul 12;50(14):3159-62. doi: 10.1021/jm070259t. Epub 2007 Jun 8. J Med Chem. 2007. PMID: 17555308
Stereoselective synthesis of 1'-functionalized-4'-thionucleosides.
Jeong LS, Gunaga P, Kim HO, Tosh DK, Lee HW, Choe SA, Moon HR, Gao ZG, Jacobson KA, Chun MW. Jeong LS, et al. Among authors: lee hw. Nucleosides Nucleotides Nucleic Acids. 2007;26(8-9):1011-4. doi: 10.1080/15257770701508588. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18058527 Free PMC article.
3,512 results