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Unveiling the antitumor potential of novel N-(substituted-phenyl)-8-methoxycoumarin-3-carboxamides as dual inhibitors of VEGFR2 kinase and cytochrome P450 for targeted treatment of hepatocellular carcinoma.
Radwan EM, Abo-Elabass E, Abd El-Baky AE, Alshwyeh HA, Almaimani RA, Almaimani G, Ibrahim IAA, Albogami A, Jaremko M, Alshawwa SZ, Saied EM. Radwan EM, et al. Among authors: saied em. Front Chem. 2023 Aug 4;11:1231030. doi: 10.3389/fchem.2023.1231030. eCollection 2023. Front Chem. 2023. PMID: 37601910 Free PMC article.
Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects.
Kalinichenko LS, Mühle C, Jia T, Anderheiden F, Datz M, Eberle AL, Eulenburg V, Granzow J, Hofer M, Hohenschild J, Huber SE, Kämpf S, Kogias G, Lacatusu L, Lugmair C, Taku SM, Meixner D, Tesch N, Praetner M, Rhein C, Sauer C, Scholz J, Ulrich F, Valenta F, Weigand E, Werner M, Tay N, Mc Veigh CJ, Haase J, Wang AL, Abdel-Hafiz L, Huston JP, Smaga I, Frankowska M, Filip M, Lourdusamy A, Kirchner P, Ekici AB, Marx LM, Suresh NP, Frischknecht R, Fejtova A, Saied EM, Arenz C, Bozec A, Wank I, Kreitz S, Hess A, Bäuerle T, Ledesma MD, Mitroi DN, Miranda AM, Oliveira TG, Gulbins E, Lenz B, Schumann G, Kornhuber J, Müller CP. Kalinichenko LS, et al. Among authors: saied em. Mol Psychiatry. 2021 Dec;26(12):7403-7416. doi: 10.1038/s41380-021-01304-w. Epub 2021 Sep 28. Mol Psychiatry. 2021. PMID: 34584229 Free PMC article.
Acetylsalicylic Acid Suppresses Alcoholism-Induced Cognitive Impairment Associated with Atorvastatin Intake by Targeting Cerebral miRNA155 and NLRP3: In Vivo, and In Silico Study.
Mohamed DI, Alaa El-Din Aly El-Waseef D, Nabih ES, El-Kharashi OA, Abd El-Kareem HF, Abo Nahas HH, Abdel-Wahab BA, Helmy YA, Alshawwa SZ, Saied EM. Mohamed DI, et al. Among authors: saied em. Pharmaceutics. 2022 Feb 27;14(3):529. doi: 10.3390/pharmaceutics14030529. Pharmaceutics. 2022. PMID: 35335908 Free PMC article.
Hepatoprotective Role of Carvedilol against Ischemic Hepatitis Associated with Acute Heart Failure via Targeting miRNA-17 and Mitochondrial Dynamics-Related Proteins: An In Vivo and In Silico Study.
Mohamed DI, Ezzat SF, Elayat WM, El-Kharashi OA, El-Kareem HFA, Nahas HHA, Abdel-Wahab BA, Alshawwa SZ, Saleh A, Helmy YA, Khairy E, Saied EM. Mohamed DI, et al. Among authors: saied em. Pharmaceuticals (Basel). 2022 Jul 5;15(7):832. doi: 10.3390/ph15070832. Pharmaceuticals (Basel). 2022. PMID: 35890131 Free PMC article.
Development of canagliflozin nanocrystals sublingual tablets in the presence of sodium caprate permeability enhancer: formulation optimization, characterization, in-vitro, in silico, and in-vivo study.
Fathy Elhabal S, El-Nabarawi MA, Abdelaal N, Elrefai MFM, Ghaffar SA, Khalifa MM, Mohie PM, Waggas DS, Hamdan AME, Alshawwa SZ, Saied EM, Elzohairy NA, Elnawawy T, Gad RA, Elfar N, Mohammed H, Khasawneh MA. Fathy Elhabal S, et al. Among authors: saied em. Drug Deliv. 2023 Dec;30(1):2241665. doi: 10.1080/10717544.2023.2241665. Drug Deliv. 2023. PMID: 37537858 Free PMC article.
Exploring the antibacterial potential of plant extracts and essential oils against Bacillus thermophilus in beet sugar for enhanced sucrose retention: a comparative assessment and implications.
Yousef MM, Zohri AA, Darwish AMG, Shamseldin A, Kabeil SA, Abdelkhalek A, Binsuwaidan R, Jaremko M, Alshwyeh HA, Hafez EE, Saied EM. Yousef MM, et al. Among authors: saied em. Front Microbiol. 2023 Jul 20;14:1219823. doi: 10.3389/fmicb.2023.1219823. eCollection 2023. Front Microbiol. 2023. PMID: 37547698 Free PMC article.
Novel 2-substituted-quinoxaline analogs with potential antiproliferative activity against breast cancer: insights into cell cycle arrest, topoisomerase II, and EGFR activity.
Salem MG, Abu El-Ata SA, Elsayed EH, Mali SN, Alshwyeh HA, Almaimani G, Almaimani RA, Almasmoum HA, Altwaijry N, Al-Olayan E, Saied EM, Youssef MF. Salem MG, et al. Among authors: saied em. RSC Adv. 2023 Nov 9;13(47):33080-33095. doi: 10.1039/d3ra06189b. eCollection 2023 Nov 7. RSC Adv. 2023. PMID: 37954422 Free PMC article.
Unveiling the interplay between NSAID-induced dysbiosis and autoimmune liver disease in children: insights into the hidden gateway to autism spectrum disorders. Evidence from ex vivo, in vivo, and clinical studies.
Mohamed DI, Abo Nahas HH, Elshaer AM, El-Waseef DAEA, El-Kharashi OA, Mohamed SMY, Sabry YG, Almaimani RA, Almasmoum HA, Altamimi AS, Ibrahim IAA, Alshawwa SZ, Jaremko M, Emwas AH, Saied EM. Mohamed DI, et al. Among authors: saied em. Front Cell Neurosci. 2023 Oct 31;17:1268126. doi: 10.3389/fncel.2023.1268126. eCollection 2023. Front Cell Neurosci. 2023. PMID: 38026692 Free PMC article.
74 results