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NRG1 fusions in breast cancer.
Howarth KD, Mirza T, Cooke SL, Chin SF, Pole JC, Turro E, Eldridge MD, Garcia RM, Rueda OM, Boursnell C, Abraham JE, Caldas C, Edwards PAW. Howarth KD, et al. Breast Cancer Res. 2021 Jan 7;23(1):3. doi: 10.1186/s13058-020-01377-5. Breast Cancer Res. 2021. PMID: 33413557 Free PMC article.
MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance.
Sale MJ, Balmanno K, Saxena J, Ozono E, Wojdyla K, McIntyre RE, Gilley R, Woroniuk A, Howarth KD, Hughes G, Dry JR, Arends MJ, Caro P, Oxley D, Ashton S, Adams DJ, Saez-Rodriguez J, Smith PD, Cook SJ. Sale MJ, et al. Among authors: howarth kd. Nat Commun. 2019 May 2;10(1):2030. doi: 10.1038/s41467-019-09438-w. Nat Commun. 2019. PMID: 31048689 Free PMC article.
Prospective Clinical Validation of the InVisionFirst-Lung Circulating Tumor DNA Assay for Molecular Profiling of Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer.
Pritchett MA, Camidge DR, Patel M, Khatri J, Boniol S, Friedman EK, Khomani A, Dalia S, Baker-Neblett K, Plagnol V, Howarth KD, Jones GR, Rosenfeld N, Morris CD, Govindan R. Pritchett MA, et al. Among authors: howarth kd. JCO Precis Oncol. 2019 Apr 25;3:PO.18.00299. doi: 10.1200/PO.18.00299. eCollection 2019. JCO Precis Oncol. 2019. PMID: 32914040 Free PMC article.
Contributions to drug resistance in glioblastoma derived from malignant cells in the sub-ependymal zone.
Piccirillo SG, Spiteri I, Sottoriva A, Touloumis A, Ber S, Price SJ, Heywood R, Francis NJ, Howarth KD, Collins VP, Venkitaraman AR, Curtis C, Marioni JC, Tavaré S, Watts C. Piccirillo SG, et al. Among authors: howarth kd. Cancer Res. 2015 Jan 1;75(1):194-202. doi: 10.1158/0008-5472.CAN-13-3131. Epub 2014 Nov 18. Cancer Res. 2015. PMID: 25406193 Free PMC article.
The relative timing of mutations in a breast cancer genome.
Newman S, Howarth KD, Greenman CD, Bignell GR, Tavaré S, Edwards PA. Newman S, et al. Among authors: howarth kd. PLoS One. 2013 Jun 10;8(6):e64991. doi: 10.1371/journal.pone.0064991. Print 2013. PLoS One. 2013. PMID: 23762276 Free PMC article.
16 results