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The DECON pilot project investigates predictive markers for successful bariatric surgery.
Seifert G, Fagnocchi L, Edozie M, Herrmann S, Baumann H, Panzeri I, Mewes S, Aicher D, Runkel M, Lässle C, Fink J, Marjanovic G, Fichtner-Feigl S, Pospisilik JA. Seifert G, et al. Among authors: fagnocchi l. Sci Rep. 2023 Aug 17;13(1):13401. doi: 10.1038/s41598-023-40452-7. Sci Rep. 2023. PMID: 37591977 Free PMC article.
Epigenetic dosage identifies two major and functionally distinct β cell subtypes.
Dror E, Fagnocchi L, Wegert V, Apostle S, Grimaldi B, Gruber T, Panzeri I, Heyne S, Höffler KD, Kreiner V, Ching R, Tsai-Hsiu Lu T, Semwal A, Johnson B, Senapati P, Lempradl A, Schones D, Imhof A, Shen H, Pospisilik JA. Dror E, et al. Among authors: fagnocchi l. Cell Metab. 2023 May 2;35(5):821-836.e7. doi: 10.1016/j.cmet.2023.03.008. Epub 2023 Mar 21. Cell Metab. 2023. PMID: 36948185 Free PMC article.
Oncogenic enhancers prime quiescent metastatic cells to escape NK immune surveillance by eliciting transcriptional memory.
Michelatti D, Beyes S, Bernardis C, Negri ML, Morelli L, Bediaga NG, Poli V, Fagnocchi L, Lago S, D'Annunzio S, Cona N, Gaspardo I, Bianchi A, Jovetic J, Gianesello M, Turdo A, D'Accardo C, Gaggianesi M, Dori M, Forcato M, Crispatzu G, Rada-Iglesias A, Sosa MS, Timmers HTM, Bicciato S, Todaro M, Tiberi L, Zippo A. Michelatti D, et al. Among authors: fagnocchi l. Nat Commun. 2024 Mar 19;15(1):2198. doi: 10.1038/s41467-024-46524-0. Nat Commun. 2024. PMID: 38503727 Free PMC article.
Developmental priming of cancer susceptibility.
Panzeri I, Fagnocchi L, Apostle S, Tompkins M, Wolfrum E, Madaj Z, Hostetter G, Liu Y, Schaefer K, Chih-Hsiang Y, Bergsma A, Drougard A, Dror E; PERMUTE; Chandler D, Schramek D, Triche TJ Jr, Pospisilik JA. Panzeri I, et al. Among authors: fagnocchi l. bioRxiv [Preprint]. 2023 Sep 15:2023.09.12.557446. doi: 10.1101/2023.09.12.557446. bioRxiv. 2023. PMID: 37745326 Free PMC article. Preprint.
An acute microglial metabolic response controls metabolism and improves memory.
Drougard A, Ma EH, Wegert V, Sheldon R, Panzeri I, Vatsa N, Apostle S, Fagnocchi L, Schaf J, Gossens K, Völker J, Pang S, Bremser A, Dror E, Giacona F, Sagar, Henderson MX, Prinz M, Jones RG, Pospisilik JA. Drougard A, et al. Among authors: fagnocchi l. bioRxiv [Preprint]. 2024 Apr 25:2023.04.03.535373. doi: 10.1101/2023.04.03.535373. bioRxiv. 2024. PMID: 37066282 Free PMC article. Preprint.
Independent phenotypic plasticity axes define distinct obesity sub-types.
Yang CH, Fagnocchi L, Apostle S, Wegert V, Casaní-Galdón S, Landgraf K, Panzeri I, Dror E, Heyne S, Wörpel T, Chandler DP, Lu D, Yang T, Gibbons E, Guerreiro R, Bras J, Thomasen M, Grunnet LG, Vaag AA, Gillberg L, Grundberg E, Conesa A, Körner A; PERMUTE; Pospisilik JA. Yang CH, et al. Among authors: fagnocchi l. Nat Metab. 2022 Sep;4(9):1150-1165. doi: 10.1038/s42255-022-00629-2. Epub 2022 Sep 12. Nat Metab. 2022. PMID: 36097183 Free PMC article.
Effective targeting of breast cancer stem cells by combined inhibition of Sam68 and Rad51.
Turdo A, Gaggianesi M, Di Franco S, Veschi V, D'Accardo C, Porcelli G, Lo Iacono M, Pillitteri I, Verona F, Militello G, Zippo A, Poli V, Fagnocchi L, Beyes S, Stella S, Lattanzio R, Faldetta N, Lentini VL, Porcasi R, Pistone G, Bongiorno MR, Stassi G, De Maria R, Todaro M. Turdo A, et al. Among authors: fagnocchi l. Oncogene. 2022 Apr;41(15):2196-2209. doi: 10.1038/s41388-022-02239-4. Epub 2022 Feb 25. Oncogene. 2022. PMID: 35217791 Free PMC article.
Murine neuronatin deficiency is associated with a hypervariable food intake and bimodal obesity.
Cimino I, Rimmington D, Tung YCL, Lawler K, Larraufie P, Kay RG, Virtue S, Lam BYH, Fagnocchi L, Ma MKL, Saudek V, Zvetkova I, Vidal-Puig A, Yeo GSH, Farooqi IS, Pospisilik JA, Gribble FM, Reimann F, O'Rahilly S, Coll AP. Cimino I, et al. Among authors: fagnocchi l. Sci Rep. 2021 Sep 2;11(1):17571. doi: 10.1038/s41598-021-96278-8. Sci Rep. 2021. PMID: 34475432 Free PMC article.
31 results