Hsu LC - Search Results

1

Mechanistic study of dual-function inhibitors targeting topoisomerase II and Rad51-mediated DNA repair pathway against castration-resistant prostate cancer.

Chiang YC, Leu WJ, Chen YC, Ye PC, Hsu YT, Hsiao YC, Hsu JL, Chan SH, Hsu LC, Huang HS, Guh JH. Chiang YC, et al. Among authors: hsu yt, hsu jl, hsu lc. Prostate. 2023 Dec;83(16):1549-1563. doi: 10.1002/pros.24613. Epub 2023 Aug 15. Prostate. 2023. PMID: 37583103

2

Pim-1 knockdown potentiates paclitaxel-induced apoptosis in human hormone-refractory prostate cancers through inhibition of NHEJ DNA repair.

Hsu JL, Leong PK, Ho YF, Hsu LC, Lu PH, Chen CS, Guh JH. Hsu JL, et al. Among authors: hsu lc. Cancer Lett. 2012 Jun 28;319(2):214-222. doi: 10.1016/j.canlet.2012.01.004. Epub 2012 Jan 17. Cancer Lett. 2012. PMID: 22261337 Free PMC article.

3

Rottlerin potentiates camptothecin-induced cytotoxicity in human hormone refractory prostate cancers through increased formation and stabilization of topoisomerase I-DNA cleavage complexes in a PKCδ-independent pathway.

Hsu JL, Ho YF, Li TK, Chen CS, Hsu LC, Guh JH. Hsu JL, et al. Among authors: hsu lc. Biochem Pharmacol. 2012 Jul 1;84(1):59-67. doi: 10.1016/j.bcp.2012.03.023. Epub 2012 Apr 2. Biochem Pharmacol. 2012. PMID: 22490701 Free PMC article.

4

Ardisianone, a natural benzoquinone, efficiently induces apoptosis in human hormone-refractory prostate cancers through mitochondrial damage stress and survivin downregulation.

Yu CC, Wu PJ, Hsu JL, Ho YF, Hsu LC, Chang YJ, Chang HS, Chen IS, Guh JH. Yu CC, et al. Among authors: hsu jl, hsu lc. Prostate. 2013 Jan;73(2):133-45. doi: 10.1002/pros.22548. Epub 2012 Jun 5. Prostate. 2013. PMID: 22674285

5

Terfenadine induces anti-proliferative and apoptotic activities in human hormone-refractory prostate cancer through histamine receptor-independent Mcl-1 cleavage and Bak up-regulation.

Wang WT, Chen YH, Hsu JL, Leu WJ, Yu CC, Chan SH, Ho YF, Hsu LC, Guh JH. Wang WT, et al. Among authors: hsu jl, hsu lc. Naunyn Schmiedebergs Arch Pharmacol. 2014 Jan;387(1):33-45. doi: 10.1007/s00210-013-0912-x. Epub 2013 Sep 19. Naunyn Schmiedebergs Arch Pharmacol. 2014. PMID: 24048439

6

Reevesioside F induces potent and efficient anti-proliferative and apoptotic activities through Na⁺/K⁺-ATPase α3 subunit-involved mitochondrial stress and amplification of caspase cascades.

Chan SH, Leu WJ, Hsu LC, Chang HS, Hwang TL, Chen IS, Chen CS, Guh JH. Chan SH, et al. Among authors: hsu lc. Biochem Pharmacol. 2013 Dec 1;86(11):1564-75. doi: 10.1016/j.bcp.2013.09.021. Epub 2013 Oct 4. Biochem Pharmacol. 2013. PMID: 24099795 Free PMC article.

7

Reevesioside A, a cardenolide glycoside, induces anticancer activity against human hormone-refractory prostate cancers through suppression of c-myc expression and induction of G1 arrest of the cell cycle.

Leu WJ, Chang HS, Chan SH, Hsu JL, Yu CC, Hsu LC, Chen IS, Guh JH. Leu WJ, et al. Among authors: hsu jl, hsu lc. PLoS One. 2014 Jan 27;9(1):e87323. doi: 10.1371/journal.pone.0087323. eCollection 2014. PLoS One. 2014. PMID: 24475272 Free PMC article.

8

A unique amidoanthraquinone derivative displays antiproliferative activity against human hormone-refractory metastatic prostate cancers through activation of LKB1-AMPK-mTOR signaling pathway.

Hsu JL, Liu SP, Lee CC, Hsu LC, Ho YF, Huang HS, Guh JH. Hsu JL, et al. Among authors: hsu lc. Naunyn Schmiedebergs Arch Pharmacol. 2014 Oct;387(10):979-90. doi: 10.1007/s00210-014-0998-9. Epub 2014 Jul 9. Naunyn Schmiedebergs Arch Pharmacol. 2014. PMID: 25005758

9

The Akt inhibitor MK-2206 enhances the cytotoxicity of paclitaxel (Taxol) and cisplatin in ovarian cancer cells.

Lin YH, Chen BY, Lai WT, Wu SF, Guh JH, Cheng AL, Hsu LC. Lin YH, et al. Among authors: hsu lc. Naunyn Schmiedebergs Arch Pharmacol. 2015 Jan;388(1):19-31. doi: 10.1007/s00210-014-1032-y. Epub 2014 Aug 28. Naunyn Schmiedebergs Arch Pharmacol. 2015. PMID: 25164962

10

Epi-reevesioside F inhibits Na+/K+-ATPase, causing cytosolic acidification, Bak activation and apoptosis in glioblastoma.

Hsu JL, Liu FL, Hsu LC, Chang HS, Leu WJ, Yu CC, Chang WL, Chen IS, Kung FL, Guh JH. Hsu JL, et al. Among authors: hsu lc. Oncotarget. 2015 Sep 15;6(27):24032-46. doi: 10.18632/oncotarget.4429. Oncotarget. 2015. PMID: 26125228 Free PMC article.

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