Gan J - Search Results

1

IFNɣ but not IFNα increases recognition of insulin defective ribosomal product-derived antigen to amplify islet autoimmunity.

Thomaidou S, Munoz Garcia A, de Lange S, Gan J, van der Slik AR, Hoeben RC, Roep BO, Carlotti F, Zaldumbide A. Thomaidou S, et al. Among authors: gan j. Diabetologia. 2023 Nov;66(11):2075-2086. doi: 10.1007/s00125-023-05991-8. Epub 2023 Aug 15. Diabetologia. 2023. PMID: 37581620 Free PMC article.

2

Highlighting the Proteasome: Using Fluorescence to Visualize Proteasome Activity and Distribution.

Gan J, Leestemaker Y, Sapmaz A, Ovaa H. Gan J, et al. Front Mol Biosci. 2019 Mar 22;6:14. doi: 10.3389/fmolb.2019.00014. eCollection 2019. Front Mol Biosci. 2019. PMID: 30968028 Free PMC article. Review.

3

Synthetic ubiquitinated proteins meet the proteasome: Distinct roles of ubiquitin in a chain.

van der Heden van Noort GJ, Gan J, Ovaa H. van der Heden van Noort GJ, et al. Among authors: gan j. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7614-7616. doi: 10.1073/pnas.1903405116. Epub 2019 Mar 29. Proc Natl Acad Sci U S A. 2019. PMID: 30926663 Free PMC article. No abstract available.

4

Total chemical synthesis of murine ISG15 and an activity-based probe with physiological binding properties.

Xin BT, Gan J, Fernandez DJ, Knobeloch KP, Geurink PP, Ovaa H. Xin BT, et al. Among authors: gan j. Org Biomol Chem. 2019 Dec 28;17(48):10148-10152. doi: 10.1039/c9ob02127b. Epub 2019 Nov 11. Org Biomol Chem. 2019. PMID: 31710063

5

Cellular Validation of a Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2.

Gan J, de Vries J, Akkermans JJLL, Mohammed Y, Tjokrodirijo RTN, de Ru AH, Kim RQ, Vargas DA, Pol V, Fasan R, van Veelen PA, Neefjes J, van Dam H, Ovaa H, Sapmaz A, Geurink PP. Gan J, et al. ACS Chem Biol. 2023 Sep 15;18(9):2003-2013. doi: 10.1021/acschembio.3c00227. Epub 2023 Aug 29. ACS Chem Biol. 2023. PMID: 37642399 Free PMC article.

6

USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism.

Gan J, Pinto-Fernández A, Flierman D, Akkermans JJLL, O'Brien DP, Greenwood H, Scott HC, Fritz G, Knobeloch KP, Neefjes J, van Dam H, Ovaa H, Ploegh HL, Kessler BM, Geurink PP, Sapmaz A. Gan J, et al. Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2315163120. doi: 10.1073/pnas.2315163120. Epub 2023 Dec 6. Proc Natl Acad Sci U S A. 2023. PMID: 38055744 Free PMC article.

7

Sirtuin 1 Inhibiting Thiocyanates (S1th)-A New Class of Isotype Selective Inhibitors of NAD⁺ Dependent Lysine Deacetylases.

Wössner N, Alhalabi Z, González J, Swyter S, Gan J, Schmidtkunz K, Zhang L, Vaquero A, Ovaa H, Einsle O, Sippl W, Jung M. Wössner N, et al. Among authors: gan j. Front Oncol. 2020 Apr 30;10:657. doi: 10.3389/fonc.2020.00657. eCollection 2020. Front Oncol. 2020. PMID: 32426286 Free PMC article.

8

Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening.

Resnick E, Bradley A, Gan J, Douangamath A, Krojer T, Sethi R, Geurink PP, Aimon A, Amitai G, Bellini D, Bennett J, Fairhead M, Fedorov O, Gabizon R, Gan J, Guo J, Plotnikov A, Reznik N, Ruda GF, Díaz-Sáez L, Straub VM, Szommer T, Velupillai S, Zaidman D, Zhang Y, Coker AR, Dowson CG, Barr HM, Wang C, Huber KVM, Brennan PE, Ovaa H, von Delft F, London N. Resnick E, et al. Among authors: gan j. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22. J Am Chem Soc. 2019. PMID: 31060360 Free PMC article.

9

Clinical characteristics of cystic encephalomalacia in children.

Fan L, Feng L, Gan J, Luo R, Qu H, Chen X. Fan L, et al. Among authors: gan j. Front Pediatr. 2024 May 22;12:1280489. doi: 10.3389/fped.2024.1280489. eCollection 2024. Front Pediatr. 2024. PMID: 38840803 Free PMC article.

10

Myocardial infarction accelerates the progression of MASH by triggering immunoinflammatory response and induction of periosti.

Xie W, Gan J, Zhou X, Tian H, Pan X, Liu W, Li X, Du J, Xu A, Zheng M, Wu F, Li Y, Lin Z. Xie W, et al. Among authors: gan j. Cell Metab. 2024 Jun 4;36(6):1269-1286.e9. doi: 10.1016/j.cmet.2024.04.020. Cell Metab. 2024. PMID: 38838640

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