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Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing.
Nat Commun. 2023 Aug 14;14(1):4761. doi: 10.1038/s41467-023-40344-4.
Nat Commun. 2023.
PMID: 37580318
Free PMC article.
Secretome screening reveals immunomodulating functions of IFNα-7, PAP and GDF-7 on regulatory T-cells.
Ding M, Malhotra R, Ottosson T, Lundqvist M, Mebrahtu A, Brengdahl J, Gehrmann U, Bäck E, Ross-Thriepland D, Isaksson I, Magnusson B, Sachsenmeier KF, Tegel H, Hober S, Uhlén M, Mayr LM, Davies R, Rockberg J, Schiavone LH.
Ding M, et al. Among authors: brengdahl j.
Sci Rep. 2021 Aug 18;11(1):16767. doi: 10.1038/s41598-021-96184-z.
Sci Rep. 2021.
PMID: 34408239
Free PMC article.
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A Phenotypic Screening Approach Using Human Treg Cells Identified Regulators of Forkhead Box p3 Expression.
Ding M, Brengdahl J, Lindqvist M, Gehrmann U, Ericson E, von Berg S, Ripa L, Malhotra R.
Ding M, et al. Among authors: brengdahl j.
ACS Chem Biol. 2019 Mar 15;14(3):543-553. doi: 10.1021/acschembio.9b00075. Epub 2019 Mar 4.
ACS Chem Biol. 2019.
PMID: 30807094
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Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X (sPLA2-X) Inhibitors.
Knerr L, Giordanetto F, Nordberg P, Pettersen D, Selmi N, Beisel HG, de la Motte H, Olsson T, Perkins TDJ, Herslöf M, Månsson Å, Dahlström M, Starke I, Broddefalk J, Saarinen G, Klingegård F, Hurt-Camejo E, Rosengren B, Brengdahl J, Jansen F, Rohman M, Sandmark J, Hallberg K, Åkerud T, Roth RG, Ahlqvist M.
Knerr L, et al. Among authors: brengdahl j.
ACS Med Chem Lett. 2018 Jun 23;9(7):594-599. doi: 10.1021/acsmedchemlett.7b00505. eCollection 2018 Jul 12.
ACS Med Chem Lett. 2018.
PMID: 30034585
Free PMC article.
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Design of Selective sPLA2-X Inhibitor (-)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid.
Giordanetto F, Knerr L, Nordberg P, Pettersen D, Selmi N, Beisel HG, de la Motte H, Månsson Å, Dahlström M, Broddefalk J, Saarinen G, Klingegård F, Hurt-Camejo E, Rosengren B, Wikström J, Wågberg M, Brengdahl J, Rohman M, Sandmark J, Åkerud T, Roth RG, Jansen F, Ahlqvist M.
Giordanetto F, et al. Among authors: brengdahl j.
ACS Med Chem Lett. 2018 Jun 23;9(7):600-605. doi: 10.1021/acsmedchemlett.7b00507. eCollection 2018 Jul 12.
ACS Med Chem Lett. 2018.
PMID: 30034586
Free PMC article.
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Novel Zn2+ Modulated GPR39 Receptor Agonists Do Not Drive Acute Insulin Secretion in Rodents.
Fjellström O, Larsson N, Yasuda S, Tsuchida T, Oguma T, Marley A, Wennberg-Huldt C, Hovdal D, Fukuda H, Yoneyama Y, Sasaki K, Johansson A, Lundqvist S, Brengdahl J, Isaacs RJ, Brown D, Geschwindner S, Benthem L, Priest C, Turnbull A.
Fjellström O, et al. Among authors: brengdahl j.
PLoS One. 2015 Dec 31;10(12):e0145849. doi: 10.1371/journal.pone.0145849. eCollection 2015.
PLoS One. 2015.
PMID: 26720709
Free PMC article.
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Validation of low-volume 1536-well assay-ready compound plates.
Eriksson H, Brengdahl J, Sandström P, Rohman M, Becker B.
Eriksson H, et al. Among authors: brengdahl j.
J Biomol Screen. 2009 Jun;14(5):468-75. doi: 10.1177/1087057109335324. Epub 2009 May 21.
J Biomol Screen. 2009.
PMID: 19470713
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A novel assay for monoacylglycerol hydrolysis suitable for high-throughput screening.
Brengdahl J, Fowler CJ.
Brengdahl J, et al.
Anal Biochem. 2006 Dec 1;359(1):40-4. doi: 10.1016/j.ab.2006.07.004. Epub 2006 Aug 4.
Anal Biochem. 2006.
PMID: 16920061
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