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Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells.
Sanmarco LM, Rone JM, Polonio CM, Fernandez Lahore G, Giovannoni F, Ferrara K, Gutierrez-Vazquez C, Li N, Sokolovska A, Plasencia A, Faust Akl C, Nanda P, Heck ES, Li Z, Lee HG, Chao CC, Rejano-Gordillo CM, Fonseca-Castro PH, Illouz T, Linnerbauer M, Kenison JE, Barilla RM, Farrenkopf D, Stevens NA, Piester G, Chung EN, Dailey L, Kuchroo VK, Hava D, Wheeler MA, Clish C, Nowarski R, Balsa E, Lora JM, Quintana FJ. Sanmarco LM, et al. Among authors: hava d. Nature. 2023 Aug;620(7975):881-889. doi: 10.1038/s41586-023-06409-6. Epub 2023 Aug 9. Nature. 2023. PMID: 37558878 Free PMC article.
Synthetic biology: at the crossroads of genetic engineering and human therapeutics-a Keystone Symposia report.
Cable J, Leonard JN, Lu TK, Xie Z, Chang MW, Fernández LÁ, Lora JM, Kaufman HL, Quintana FJ, Geiger R, F Lesser C, Lynch JP, Hava DL, Cornish VW, Lee GK, DiAndreth B, Fero M, Srivastava R, De Coster T, Roybal KT, Rackham OJL, Kiani S, Zhu I, Hernandez-Lopez RA, Guo T, Chen WCW. Cable J, et al. Ann N Y Acad Sci. 2021 Dec;1506(1):98-117. doi: 10.1111/nyas.14710. Epub 2021 Nov 16. Ann N Y Acad Sci. 2021. PMID: 34786712 Review.
Serum lipids regulate dendritic cell CD1 expression and function.
Leslie DS, Dascher CC, Cembrola K, Townes MA, Hava DL, Hugendubler LC, Mueller E, Fox L, Roura-Mir C, Moody DB, Vincent MS, Gumperz JE, Illarionov PA, Besra GS, Reynolds CG, Brenner MB. Leslie DS, et al. Among authors: hava dl. Immunology. 2008 Nov;125(3):289-301. doi: 10.1111/j.1365-2567.2008.02842.x. Epub 2008 Apr 28. Immunology. 2008. PMID: 18445008 Free PMC article.
An engineered bacterial therapeutic lowers urinary oxalate in preclinical models and in silico simulations of enteric hyperoxaluria.
Lubkowicz D, Horvath NG, James MJ, Cantarella P, Renaud L, Bergeron CG, Shmueli RB, Anderson C, Gao JR, Kurtz CB, Perreault M, Charbonneau MR, Isabella VM, Hava DL. Lubkowicz D, et al. Among authors: hava dl. Mol Syst Biol. 2022 Mar;18(3):e10539. doi: 10.15252/msb.202110539. Mol Syst Biol. 2022. PMID: 35253995 Free PMC article.
36 results