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Cas9-mediated knockout of Ndrg2 enhances the regenerative potential of dendritic cells for wound healing.
Henn D, Zhao D, Sivaraj D, Trotsyuk A, Bonham CA, Fischer KS, Kehl T, Fehlmann T, Greco AH, Kussie HC, Moortgat Illouz SE, Padmanabhan J, Barrera JA, Kneser U, Lenhof HP, Januszyk M, Levi B, Keller A, Longaker MT, Chen K, Qi LS, Gurtner GC. Henn D, et al. Among authors: greco ah. Nat Commun. 2023 Aug 7;14(1):4729. doi: 10.1038/s41467-023-40519-z. Nat Commun. 2023. PMID: 37550295 Free PMC article.
Disrupting biological sensors of force promotes tissue regeneration in large organisms.
Chen K, Kwon SH, Henn D, Kuehlmann BA, Tevlin R, Bonham CA, Griffin M, Trotsyuk AA, Borrelli MR, Noishiki C, Padmanabhan J, Barrera JA, Maan ZN, Dohi T, Mays CJ, Greco AH, Sivaraj D, Lin JQ, Fehlmann T, Mermin-Bunnell AM, Mittal S, Hu MS, Zamaleeva AI, Keller A, Rajadas J, Longaker MT, Januszyk M, Gurtner GC. Chen K, et al. Among authors: greco ah. Nat Commun. 2021 Sep 6;12(1):5256. doi: 10.1038/s41467-021-25410-z. Nat Commun. 2021. PMID: 34489407 Free PMC article.
Xenogeneic skin transplantation promotes angiogenesis and tissue regeneration through activated Trem2+ macrophages.
Henn D, Chen K, Fehlmann T, Trotsyuk AA, Sivaraj D, Maan ZN, Bonham CA Jr, Barrera JA, Mays CJ, Greco AH, Moortgat Illouz SE, Lin JQ, Steele SR, Foster DS, Padmanabhan J, Momeni A, Nguyen D, Wan DC, Kneser U, Januszyk M, Keller A, Longaker MT, Gurtner GC. Henn D, et al. Among authors: greco ah. Sci Adv. 2021 Dec 3;7(49):eabi4528. doi: 10.1126/sciadv.abi4528. Epub 2021 Dec 1. Sci Adv. 2021. PMID: 34851663 Free PMC article.
Enrichment of Nanofiber Hydrogel Composite with Fractionated Fat Promotes Regenerative Macrophage Polarization and Vascularization for Soft-Tissue Engineering.
Henn D, Fischer KS, Chen K, Greco AH, Martin RA, Sivaraj D, Trotsyuk AA, Mao HQ, Reddy SK, Kneser U, Gurtner GC, Schmidt VJ, Sacks JM. Henn D, et al. Among authors: greco ah. Plast Reconstr Surg. 2022 Mar 1;149(3):433e-444e. doi: 10.1097/PRS.0000000000008872. Plast Reconstr Surg. 2022. PMID: 35196680
Pullulan-Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings.
Chen K, Sivaraj D, Davitt MF, Leeolou MC, Henn D, Steele SR, Huskins SL, Trotsyuk AA, Kussie HC, Greco AH, Padmanabhan J, Perrault DP, Zamaleeva AI, Longaker MT, Gurtner GC. Chen K, et al. Among authors: greco ah. Wound Repair Regen. 2022 May;30(3):397-408. doi: 10.1111/wrr.13012. Epub 2022 Apr 18. Wound Repair Regen. 2022. PMID: 35384131 Free PMC article.
Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting.
Chen K, Henn D, Januszyk M, Barrera JA, Noishiki C, Bonham CA, Griffin M, Tevlin R, Carlomagno T, Shannon T, Fehlmann T, Trotsyuk AA, Padmanabhan J, Sivaraj D, Perrault DP, Zamaleeva AI, Mays CJ, Greco AH, Kwon SH, Leeolou MC, Huskins SL, Steele SR, Fischer KS, Kussie HC, Mittal S, Mermin-Bunnell AM, Diaz Deleon NM, Lavin C, Keller A, Longaker MT, Gurtner GC. Chen K, et al. Among authors: greco ah. Sci Transl Med. 2022 May 18;14(645):eabj9152. doi: 10.1126/scitranslmed.abj9152. Epub 2022 May 18. Sci Transl Med. 2022. PMID: 35584231
Nitric oxide-releasing gel accelerates healing in a diabetic murine splinted excisional wound model.
Sivaraj D, Noishiki C, Kosaric N, Kiwanuka H, Kussie HC, Henn D, Fischer KS, Trotsyuk AA, Greco AH, Kuehlmann BA, Quintero F, Leeolou MC, Granoski MB, Hostler AC, Hahn WW, Januszyk M, Murad F, Chen K, Gurtner GC. Sivaraj D, et al. Among authors: greco ah. Front Med (Lausanne). 2023 Mar 2;10:1060758. doi: 10.3389/fmed.2023.1060758. eCollection 2023. Front Med (Lausanne). 2023. PMID: 36999070 Free PMC article.