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Early syphilis in Guangzhou, China: presentation, molecular detection of Treponema pallidum , and genomic sequences in clinical specimens and isolates obtained by rabbit infectivity testing.
Yang L, Zhang X, Chen W, Seña AC, Zheng H, Jiang Y, Zhao P, Chen R, Wang L, Ke W, Salazar JC, Parr JB, Tucker JD, Hawley KL, Caimano MJ, Hennelly CM, Aghakanian F, Zhang F, Chen JS, Moody MA, Radolf JD, Yang B. Yang L, et al. Among authors: caimano mj. medRxiv [Preprint]. 2023 Oct 19:2023.10.17.23297169. doi: 10.1101/2023.10.17.23297169. medRxiv. 2023. PMID: 37905017 Free PMC article. Preprint.
A unique borrelial protein facilitates microbial immune evasion.
Foor SD, Brangulis K, Shakya AK, Rana VS, Bista S, Kitsou C, Ronzetti M, Alreja AB, Linden SB, Altieri AS, Baljinnyam B, Akopjana I, Nelson DC, Simeonov A, Herzberg O, Caimano MJ, Pal U. Foor SD, et al. Among authors: caimano mj. mBio. 2023 Oct 31;14(5):e0213523. doi: 10.1128/mbio.02135-23. Epub 2023 Oct 13. mBio. 2023. PMID: 37830812 Free PMC article.
Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326).
Ferguson MR, Delgado KN, McBride S, Orbe IC, La Vake CJ, Caimano MJ, Mendez Q, Moraes TF, Schryvers AB, Moody MA, Radolf JD, Weiner MP, Hawley KL. Ferguson MR, et al. Among authors: caimano mj. Front Immunol. 2023 Aug 22;14:1222267. doi: 10.3389/fimmu.2023.1222267. eCollection 2023. Front Immunol. 2023. PMID: 37675118 Free PMC article.
Clinical and genomic diversity of Treponema pallidum subsp. pallidum: A global, multi-center study of early syphilis to inform vaccine research.
Seña AC, Matoga MM, Yang L, Lopez-Medina E, Aghakanian F, Chen JS, Bettin EB, Caimano MJ, Chen W, Garcia-Luna JA, Hennelly CM, Jiang Y, Juliano JJ, Pospíšilová P, Ramirez L, Šmajs D, Tucker JD, Cely FV, Zheng H, Hoffman IF, Yang B, Moody MA, Hawley KL, Salazar JC, Radolf JD, Parr JB. Seña AC, et al. Among authors: caimano mj. medRxiv [Preprint]. 2023 Jul 24:2023.07.19.23291250. doi: 10.1101/2023.07.19.23291250. medRxiv. 2023. PMID: 37546832 Free PMC article. Preprint.
Extracellular Loops of the Treponema pallidum FadL Orthologs TP0856 and TP0858 Elicit IgG Antibodies and IgG+-Specific B-Cells in the Rabbit Model of Experimental Syphilis.
Delgado KN, Montezuma-Rusca JM, Orbe IC, Caimano MJ, La Vake CJ, Luthra A, Hennelly CM, Nindo FN, Meyer JW, Jones LD, Parr JB, Salazar JC, Moody MA, Radolf JD, Hawley KL. Delgado KN, et al. Among authors: caimano mj. mBio. 2022 Aug 30;13(4):e0163922. doi: 10.1128/mbio.01639-22. Epub 2022 Jul 12. mBio. 2022. PMID: 35862766 Free PMC article.
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