Luscher B - Search Results

1

Sequential deregulation of histone marks, chromatin accessibility and gene expression in response to PROTAC-induced degradation of ASH2L.

Barsoum M, Sayadi-Boroujeni R, Stenzel AT, Bussmann P, Lüscher-Firzlaff J, Lüscher B. Barsoum M, et al. Among authors: luscher b. Sci Rep. 2023 Dec 19;13(1):22565. doi: 10.1038/s41598-023-49284-x. Sci Rep. 2023. PMID: 38114530 Free PMC article.

2

GABA_A receptors as targets for treating affective and cognitive symptoms of depression.

Luscher B, Maguire JL, Rudolph U, Sibille E. Luscher B, et al. Trends Pharmacol Sci. 2023 Sep;44(9):586-600. doi: 10.1016/j.tips.2023.06.009. Epub 2023 Aug 3. Trends Pharmacol Sci. 2023. PMID: 37543478 Review.

3

Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication.

Krieg S, Pott F, Potthoff L, Verheirstraeten M, Bütepage M, Golzmann A, Lippok B, Goffinet C, Lüscher B, Korn P. Krieg S, et al. Among authors: luscher b. Cell Mol Life Sci. 2023 Feb 25;80(3):72. doi: 10.1007/s00018-023-04717-8. Cell Mol Life Sci. 2023. PMID: 36840772 Free PMC article.

4

[1,2,4]Triazolo[3,4-b]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes.

Murthy S, Nizi MG, Maksimainen MM, Massari S, Alaviuhkola J, Lippok BE, Vagaggini C, Sowa ST, Galera-Prat A, Ashok Y, Venkannagari H, Prunskaite-Hyyryläinen R, Dreassi E, Lüscher B, Korn P, Tabarrini O, Lehtiö L. Murthy S, et al. Among authors: luscher b. J Med Chem. 2023 Jan 26;66(2):1301-1320. doi: 10.1021/acs.jmedchem.2c01460. Epub 2023 Jan 4. J Med Chem. 2023. PMID: 36598465 Free PMC article.

5

Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes reduces chromatin accessibility at promoters.

Barsoum M, Stenzel AT, Bochyńska A, Kuo CC, Tsompanidis A, Sayadi-Boroujeni R, Bussmann P, Lüscher-Firzlaff J, Costa IG, Lüscher B. Barsoum M, et al. Among authors: luscher b. Sci Rep. 2022 Dec 13;12(1):21506. doi: 10.1038/s41598-022-25881-0. Sci Rep. 2022. PMID: 36513698 Free PMC article.

6

Hyperuricemia during Pregnancy Leads to a Preeclampsia-Like Phenotype in Mice.

Lüscher BP, Schoeberlein A, Surbek DV, Baumann MU. Lüscher BP, et al. Cells. 2022 Nov 21;11(22):3703. doi: 10.3390/cells11223703. Cells. 2022. PMID: 36429132 Free PMC article.

7

Protein and RNA ADP-ribosylation detection is influenced by sample preparation and reagents used.

Weixler L, Ikenga NJ, Voorneveld J, Aydin G, Bolte TM, Momoh J, Bütepage M, Golzmann A, Lüscher B, Filippov DV, Žaja R, Feijs KL. Weixler L, et al. Among authors: luscher b. Life Sci Alliance. 2022 Nov 11;6(1):e202201455. doi: 10.26508/lsa.202201455. Print 2023 Jan. Life Sci Alliance. 2022. PMID: 36368907 Free PMC article.

8

Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes.

Bochyńska A, Stenzel AT, Sayadi Boroujeni R, Kuo CC, Barsoum M, Liang W, Bussmann P, Costa IG, Lüscher-Firzlaff J, Lüscher B. Bochyńska A, et al. Among authors: luscher b. Nucleic Acids Res. 2022 Aug 12;50(14):7889-7905. doi: 10.1093/nar/gkac591. Nucleic Acids Res. 2022. PMID: 35819198 Free PMC article.

9

Intracellular mono-ADP-ribosyltransferases at the host-virus interphase.

Lüscher B, Verheirstraeten M, Krieg S, Korn P. Lüscher B, et al. Cell Mol Life Sci. 2022 May 10;79(6):288. doi: 10.1007/s00018-022-04290-6. Cell Mol Life Sci. 2022. PMID: 35536484 Free PMC article. Review.

10

Potent 2,3-dihydrophthalazine-1,4-dione derivatives as dual inhibitors for mono-ADP-ribosyltransferases PARP10 and PARP15.

Nizi MG, Maksimainen MM, Murthy S, Massari S, Alaviuhkola J, Lippok BE, Sowa ST, Galera-Prat A, Prunskaite-Hyyryläinen R, Lüscher B, Korn P, Lehtiö L, Tabarrini O. Nizi MG, et al. Among authors: luscher b. Eur J Med Chem. 2022 Jul 5;237:114362. doi: 10.1016/j.ejmech.2022.114362. Epub 2022 Apr 19. Eur J Med Chem. 2022. PMID: 35500474

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