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Design of a mucin-selective protease for targeted degradation of cancer-associated mucins.
Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malaker SA, Kuo A, George BM, Miller CL, Casey KM, Vilches-Moure JG, Ferracane MJ, Weaver VM, Läubli H, Bertozzi CR. Pedram K, et al. Among authors: weaver vm. Nat Biotechnol. 2024 Apr;42(4):597-607. doi: 10.1038/s41587-023-01840-6. Epub 2023 Aug 3. Nat Biotechnol. 2024. PMID: 37537499 Free PMC article.
The cancer glycocalyx mechanically primes integrin-mediated growth and survival.
Paszek MJ, DuFort CC, Rossier O, Bainer R, Mouw JK, Godula K, Hudak JE, Lakins JN, Wijekoon AC, Cassereau L, Rubashkin MG, Magbanua MJ, Thorn KS, Davidson MW, Rugo HS, Park JW, Hammer DA, Giannone G, Bertozzi CR, Weaver VM. Paszek MJ, et al. Among authors: weaver vm. Nature. 2014 Jul 17;511(7509):319-25. doi: 10.1038/nature13535. Epub 2014 Jun 25. Nature. 2014. PMID: 25030168 Free PMC article.
Tissue Force Programs Cell Fate and Tumor Aggression.
Northey JJ, Przybyla L, Weaver VM. Northey JJ, et al. Among authors: weaver vm. Cancer Discov. 2017 Nov;7(11):1224-1237. doi: 10.1158/2159-8290.CD-16-0733. Epub 2017 Oct 16. Cancer Discov. 2017. PMID: 29038232 Free PMC article. Review.
New Horizons in Advocacy Engaged Physical Sciences and Oncology Research.
Samson S, Northey JJ, Plaks V, Baas C, Dean I, LaBarge MA, Goga A, Van't Veer LJ, Weaver VM. Samson S, et al. Among authors: weaver vm. Trends Cancer. 2018 Apr;4(4):260-264. doi: 10.1016/j.trecan.2018.02.002. Epub 2018 Mar 15. Trends Cancer. 2018. PMID: 29606307 Free PMC article. Review.
A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma.
Barnes JM, Kaushik S, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lee M, Lee HW, Tung JC, Maller O, Barrett AS, Lu KV, Lakins JN, Hansen KC, Obernier K, Alvarez-Buylla A, Bergers G, Phillips JJ, Nam DH, Bertozzi CR, Weaver VM. Barnes JM, et al. Among authors: weaver vm. Nat Cell Biol. 2018 Oct;20(10):1203-1214. doi: 10.1038/s41556-018-0183-3. Epub 2018 Sep 10. Nat Cell Biol. 2018. PMID: 30202050 Free PMC article.
Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217.
Northey JJ, Barrett AS, Acerbi I, Hayward MK, Talamantes S, Dean IS, Mouw JK, Ponik SM, Lakins JN, Huang PJ, Wu J, Shi Q, Samson S, Keely PJ, Mukhtar RA, Liphardt JT, Shepherd JA, Hwang ES, Chen YY, Hansen KC, Littlepage LE, Weaver VM. Northey JJ, et al. Among authors: weaver vm. J Clin Invest. 2020 Nov 2;130(11):5721-5737. doi: 10.1172/JCI129249. J Clin Invest. 2020. PMID: 32721948 Free PMC article. Clinical Trial.
236 results