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Design of a mucin-selective protease for targeted degradation of cancer-associated mucins.
Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malaker SA, Kuo A, George BM, Miller CL, Casey KM, Vilches-Moure JG, Ferracane MJ, Weaver VM, Läubli H, Bertozzi CR. Pedram K, et al. Among authors: george bm. Nat Biotechnol. 2024 Apr;42(4):597-607. doi: 10.1038/s41587-023-01840-6. Epub 2023 Aug 3. Nat Biotechnol. 2024. PMID: 37537499 Free PMC article.
Small RNAs are modified with N-glycans and displayed on the surface of living cells.
Flynn RA, Pedram K, Malaker SA, Batista PJ, Smith BAH, Johnson AG, George BM, Majzoub K, Villalta PW, Carette JE, Bertozzi CR. Flynn RA, et al. Among authors: george bm. Cell. 2021 Jun 10;184(12):3109-3124.e22. doi: 10.1016/j.cell.2021.04.023. Epub 2021 May 17. Cell. 2021. PMID: 34004145 Free PMC article.
Single-cell analysis reveals T cell infiltration in old neurogenic niches.
Dulken BW, Buckley MT, Navarro Negredo P, Saligrama N, Cayrol R, Leeman DS, George BM, Boutet SC, Hebestreit K, Pluvinage JV, Wyss-Coray T, Weissman IL, Vogel H, Davis MM, Brunet A. Dulken BW, et al. Among authors: george bm. Nature. 2019 Jul;571(7764):205-210. doi: 10.1038/s41586-019-1362-5. Epub 2019 Jul 3. Nature. 2019. PMID: 31270459 Free PMC article.
Ageing hallmarks exhibit organ-specific temporal signatures.
Schaum N, Lehallier B, Hahn O, Pálovics R, Hosseinzadeh S, Lee SE, Sit R, Lee DP, Losada PM, Zardeneta ME, Fehlmann T, Webber JT, McGeever A, Calcuttawala K, Zhang H, Berdnik D, Mathur V, Tan W, Zee A, Tan M; Tabula Muris Consortium; Pisco AO, Karkanias J, Neff NF, Keller A, Darmanis S, Quake SR, Wyss-Coray T. Schaum N, et al. Nature. 2020 Jul;583(7817):596-602. doi: 10.1038/s41586-020-2499-y. Epub 2020 Jul 15. Nature. 2020. PMID: 32669715 Free PMC article.
Engagement of MHC class I by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy.
Barkal AA, Weiskopf K, Kao KS, Gordon SR, Rosental B, Yiu YY, George BM, Markovic M, Ring NG, Tsai JM, McKenna KM, Ho PY, Cheng RZ, Chen JY, Barkal LJ, Ring AM, Weissman IL, Maute RL. Barkal AA, et al. Among authors: george bm. Nat Immunol. 2018 Jan;19(1):76-84. doi: 10.1038/s41590-017-0004-z. Epub 2017 Nov 27. Nat Immunol. 2018. PMID: 29180808 Free PMC article.
Molecular hallmarks of heterochronic parabiosis at single-cell resolution.
Pálovics R, Keller A, Schaum N, Tan W, Fehlmann T, Borja M, Kern F, Bonanno L, Calcuttawala K, Webber J, McGeever A; Tabula Muris Consortium; Luo J, Pisco AO, Karkanias J, Neff NF, Darmanis S, Quake SR, Wyss-Coray T. Pálovics R, et al. Nature. 2022 Mar;603(7900):309-314. doi: 10.1038/s41586-022-04461-2. Epub 2022 Mar 2. Nature. 2022. PMID: 35236985 Free PMC article.
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes.
Sockolosky JT, Trotta E, Parisi G, Picton L, Su LL, Le AC, Chhabra A, Silveria SL, George BM, King IC, Tiffany MR, Jude K, Sibener LV, Baker D, Shizuru JA, Ribas A, Bluestone JA, Garcia KC. Sockolosky JT, et al. Among authors: george bm. Science. 2018 Mar 2;359(6379):1037-1042. doi: 10.1126/science.aar3246. Science. 2018. PMID: 29496879 Free PMC article.
Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors.
Krampitz GW, George BM, Willingham SB, Volkmer JP, Weiskopf K, Jahchan N, Newman AM, Sahoo D, Zemek AJ, Yanovsky RL, Nguyen JK, Schnorr PJ, Mazur PK, Sage J, Longacre TA, Visser BC, Poultsides GA, Norton JA, Weissman IL. Krampitz GW, et al. Among authors: george bm. Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4464-9. doi: 10.1073/pnas.1600007113. Epub 2016 Mar 31. Proc Natl Acad Sci U S A. 2016. PMID: 27035983 Free PMC article.
49 results