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Design of a mucin-selective protease for targeted degradation of cancer-associated mucins.
Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malaker SA, Kuo A, George BM, Miller CL, Casey KM, Vilches-Moure JG, Ferracane MJ, Weaver VM, Läubli H, Bertozzi CR. Pedram K, et al. Among authors: ferracane mj. Nat Biotechnol. 2024 Apr;42(4):597-607. doi: 10.1038/s41587-023-01840-6. Epub 2023 Aug 3. Nat Biotechnol. 2024. PMID: 37537499 Free PMC article.
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins.
Malaker SA, Pedram K, Ferracane MJ, Bensing BA, Krishnan V, Pett C, Yu J, Woods EC, Kramer JR, Westerlind U, Dorigo O, Bertozzi CR. Malaker SA, et al. Among authors: ferracane mj. Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7278-7287. doi: 10.1073/pnas.1813020116. Epub 2019 Mar 25. Proc Natl Acad Sci U S A. 2019. PMID: 30910957 Free PMC article.
Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE.
Chongsaritsinsuk J, Steigmeyer AD, Mahoney KE, Rosenfeld MA, Lucas TM, Smith CM, Li A, Ince D, Kearns FL, Battison AS, Hollenhorst MA, Judy Shon D, Tiemeyer KH, Attah V, Kwon C, Bertozzi CR, Ferracane MJ, Lemmon MA, Amaro RE, Malaker SA. Chongsaritsinsuk J, et al. Among authors: ferracane mj. Nat Commun. 2023 Oct 4;14(1):6169. doi: 10.1038/s41467-023-41756-y. Nat Commun. 2023. PMID: 37794035 Free PMC article.
12 results