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Genome-wide association studies of human and rat BMI converge on synapse, epigenome, and hormone signaling networks.
Wright SN, Leger BS, Rosenthal SB, Liu SN, Jia T, Chitre AS, Polesskaya O, Holl K, Gao J, Cheng R, Garcia Martinez A, George A, Gileta AF, Han W, Netzley AH, King CP, Lamparelli A, Martin C, St Pierre CL, Wang T, Bimschleger H, Richards J, Ishiwari K, Chen H, Flagel SB, Meyer P, Robinson TE, Solberg Woods LC, Kreisberg JF, Ideker T, Palmer AA. Wright SN, et al. Among authors: palmer aa. Cell Rep. 2023 Aug 29;42(8):112873. doi: 10.1016/j.celrep.2023.112873. Epub 2023 Jul 31. Cell Rep. 2023. PMID: 37527041 Free PMC article.
Genome-wide association study in a rat model of temperament identifies multiple loci for exploratory locomotion and anxiety-like traits.
Chitre AS, Hebda-Bauer EK, Blandino P, Bimschleger H, Nguyen KM, Maras P, Li F, Ozel AB, Pan Y, Polesskaya O, Cheng R, Flagel SB, Watson SJ Jr, Li J, Akil H, Palmer AA. Chitre AS, et al. Among authors: palmer aa. Front Genet. 2023 Jan 11;13:1003074. doi: 10.3389/fgene.2022.1003074. eCollection 2022. Front Genet. 2023. PMID: 36712851 Free PMC article.
Genome-wide association study finds multiple loci associated with intraocular pressure in HS rats.
Fowler S, Wang T, Munro D, Kumar A, Chitre AS, Hollingsworth TJ, Garcia Martinez A, St Pierre CL, Bimschleger H, Gao J, Cheng R, Mohammadi P, Chen H, Palmer AA, Polesskaya O, Jablonski MM. Fowler S, et al. Among authors: palmer aa. Front Genet. 2023 Jan 30;13:1029058. doi: 10.3389/fgene.2022.1029058. eCollection 2022. Front Genet. 2023. PMID: 36793389 Free PMC article.
Automated quantitative trait locus analysis (AutoQTL).
Freda PJ, Ghosh A, Zhang E, Luo T, Chitre AS, Polesskaya O, St Pierre CL, Gao J, Martin CD, Chen H, Garcia-Martinez AG, Wang T, Han W, Ishiwari K, Meyer P, Lamparelli A, King CP, Palmer AA, Li R, Moore JH. Freda PJ, et al. Among authors: palmer aa. BioData Min. 2023 Apr 10;16(1):14. doi: 10.1186/s13040-023-00331-3. BioData Min. 2023. PMID: 37038201 Free PMC article.
Environmental enrichment promotes adaptive responding during tests of behavioral regulation in male heterogeneous stock rats.
Ishiwari K, King CP, Martin CD, Tripi JA, George AM, Lamparelli AC, Chitre A, Polesskaya O, Richards JB, Woods LCS, Gancarz A, Palmer AA, Dietz DM, Mitchell SH, Meyer PJ. Ishiwari K, et al. Among authors: palmer aa. bioRxiv [Preprint]. 2023 Aug 1:2023.06.30.547228. doi: 10.1101/2023.06.30.547228. bioRxiv. 2023. PMID: 37503161 Free PMC article. Updated. Preprint.
Environmental enrichment promotes adaptive responding during tests of behavioral regulation in male heterogeneous stock rats.
Ishiwari K, King CP, Martin CD, Tripi JA, George AM, Lamparelli AC, Chitre AS, Polesskaya O, Richards JB, Solberg Woods LC, Gancarz AM, Palmer AA, Dietz DM, Mitchell SH, Meyer PJ. Ishiwari K, et al. Among authors: palmer aa. Sci Rep. 2024 Feb 20;14(1):4182. doi: 10.1038/s41598-024-53943-y. Sci Rep. 2024. PMID: 38378969 Free PMC article.
A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats.
de Jong TV, Pan Y, Rastas P, Munro D, Tutaj M, Akil H, Benner C, Chen D, Chitre AS, Chow W, Colonna V, Dalgard CL, Demos WM, Doris PA, Garrison E, Geurts AM, Gunturkun HM, Guryev V, Hourlier T, Howe K, Huang J, Kalbfleisch T, Kim P, Li L, Mahaffey S, Martin FJ, Mohammadi P, Ozel AB, Polesskaya O, Pravenec M, Prins P, Sebat J, Smith JR, Solberg Woods LC, Tabakoff B, Tracey A, Uliano-Silva M, Villani F, Wang H, Sharp BM, Telese F, Jiang Z, Saba L, Wang X, Murphy TD, Palmer AA, Kwitek AE, Dwinell MR, Williams RW, Li JZ, Chen H. de Jong TV, et al. Among authors: palmer aa. Cell Genom. 2024 Apr 10;4(4):100527. doi: 10.1016/j.xgen.2024.100527. Epub 2024 Mar 26. Cell Genom. 2024. PMID: 38537634 Free PMC article.
Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes.
Toikumo S, Jennings MV, Pham BK, Lee H, Mallard TT, Bianchi SB, Meredith JJ, Vilar-Ribó L, Xu H, Hatoum AS, Johnson EC, Pazdernik V, Jinwala Z, Pakala SR, Leger BS, Niarchou M, Ehinmowo M; Penn Medicine BioBank, Million Veteran Program, PsycheMERGE Substance Use Disorder Workgroup; Jenkins GD, Batzler A, Pendegraft R, Palmer AA, Zhou H, Biernacka JM, Coombes BJ, Gelernter J, Xu K, Hancock DB, Cox NJ, Smoller JW, Davis LK, Justice AC, Kranzler HR, Kember RL, Sanchez-Roige S. Toikumo S, et al. Among authors: palmer aa. medRxiv [Preprint]. 2023 Sep 18:2023.03.27.23287713. doi: 10.1101/2023.03.27.23287713. medRxiv. 2023. PMID: 37034728 Free PMC article. Updated. Preprint.
293 results