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Genome-wide association studies of human and rat BMI converge on synapse, epigenome, and hormone signaling networks.
Wright SN, Leger BS, Rosenthal SB, Liu SN, Jia T, Chitre AS, Polesskaya O, Holl K, Gao J, Cheng R, Garcia Martinez A, George A, Gileta AF, Han W, Netzley AH, King CP, Lamparelli A, Martin C, St Pierre CL, Wang T, Bimschleger H, Richards J, Ishiwari K, Chen H, Flagel SB, Meyer P, Robinson TE, Solberg Woods LC, Kreisberg JF, Ideker T, Palmer AA. Wright SN, et al. Among authors: holl k. Cell Rep. 2023 Aug 29;42(8):112873. doi: 10.1016/j.celrep.2023.112873. Epub 2023 Jul 31. Cell Rep. 2023. PMID: 37527041 Free PMC article.
Genome-Wide Association Study in 3,173 Outbred Rats Identifies Multiple Loci for Body Weight, Adiposity, and Fasting Glucose.
Chitre AS, Polesskaya O, Holl K, Gao J, Cheng R, Bimschleger H, Garcia Martinez A, George T, Gileta AF, Han W, Horvath A, Hughson A, Ishiwari K, King CP, Lamparelli A, Versaggi CL, Martin C, St Pierre CL, Tripi JA, Wang T, Chen H, Flagel SB, Meyer P, Richards J, Robinson TE, Palmer AA, Solberg Woods LC. Chitre AS, et al. Among authors: holl k. Obesity (Silver Spring). 2020 Oct;28(10):1964-1973. doi: 10.1002/oby.22927. Epub 2020 Aug 29. Obesity (Silver Spring). 2020. PMID: 32860487 Free PMC article.
Genome-Wide Association Study on Three Behaviors Tested in an Open Field in Heterogeneous Stock Rats Identifies Multiple Loci Implicated in Psychiatric Disorders.
Gunturkun MH, Wang T, Chitre AS, Garcia Martinez A, Holl K, St Pierre C, Bimschleger H, Gao J, Cheng R, Polesskaya O, Solberg Woods LC, Palmer AA, Chen H. Gunturkun MH, et al. Among authors: holl k. Front Psychiatry. 2022 Feb 14;13:790566. doi: 10.3389/fpsyt.2022.790566. eCollection 2022. Front Psychiatry. 2022. PMID: 35237186 Free PMC article.
An exponential increase in QTL detection with an increased sample size.
Chitre AS, Polesskaya O, Munro D, Cheng R, Mohammadi P, Holl K, Gao J, Bimschleger H, Martinez AG, George AM, Gileta AF, Han W, Horvath A, Hughson A, Ishiwari K, King CP, Lamparelli A, Versaggi CL, Martin CD, St Pierre CL, Tripi JA, Richards JB, Wang T, Chen H, Flagel SB, Meyer P, Robinson TE, Solberg Woods LC, Palmer AA. Chitre AS, et al. Among authors: holl k. Genetics. 2023 May 26;224(2):iyad054. doi: 10.1093/genetics/iyad054. Genetics. 2023. PMID: 36974931 Free PMC article.
Sept8/SEPTIN8 involvement in cellular structure and kidney damage is identified by genetic mapping and a novel human tubule hypoxic model.
Keele GR, Prokop JW, He H, Holl K, Littrell J, Deal AW, Kim Y, Kyle PB, Attipoe E, Johnson AC, Uhl KL, Sirpilla OL, Jahanbakhsh S, Robinson M, Levy S, Valdar W, Garrett MR, Solberg Woods LC. Keele GR, et al. Among authors: holl k. Sci Rep. 2021 Jan 22;11(1):2071. doi: 10.1038/s41598-021-81550-8. Sci Rep. 2021. PMID: 33483609 Free PMC article.
Transcriptome-wide analyses of adipose tissue in outbred rats reveal genetic regulatory mechanisms relevant for human obesity.
Crouse WL, Das SK, Le T, Keele G, Holl K, Seshie O, Craddock AL, Sharma NK, Comeau ME, Langefeld CD, Hawkins GA, Mott R, Valdar W, Solberg Woods LC. Crouse WL, et al. Among authors: holl k. Physiol Genomics. 2022 Jun 1;54(6):206-219. doi: 10.1152/physiolgenomics.00172.2021. Epub 2022 Apr 25. Physiol Genomics. 2022. PMID: 35467982 Free PMC article.
149 results