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Genome-wide association studies of human and rat BMI converge on synapse, epigenome, and hormone signaling networks.
Wright SN, Leger BS, Rosenthal SB, Liu SN, Jia T, Chitre AS, Polesskaya O, Holl K, Gao J, Cheng R, Garcia Martinez A, George A, Gileta AF, Han W, Netzley AH, King CP, Lamparelli A, Martin C, St Pierre CL, Wang T, Bimschleger H, Richards J, Ishiwari K, Chen H, Flagel SB, Meyer P, Robinson TE, Solberg Woods LC, Kreisberg JF, Ideker T, Palmer AA. Wright SN, et al. Among authors: gao j. Cell Rep. 2023 Aug 29;42(8):112873. doi: 10.1016/j.celrep.2023.112873. Epub 2023 Jul 31. Cell Rep. 2023. PMID: 37527041 Free PMC article.
Genome-Wide Association Study in 3,173 Outbred Rats Identifies Multiple Loci for Body Weight, Adiposity, and Fasting Glucose.
Chitre AS, Polesskaya O, Holl K, Gao J, Cheng R, Bimschleger H, Garcia Martinez A, George T, Gileta AF, Han W, Horvath A, Hughson A, Ishiwari K, King CP, Lamparelli A, Versaggi CL, Martin C, St Pierre CL, Tripi JA, Wang T, Chen H, Flagel SB, Meyer P, Richards J, Robinson TE, Palmer AA, Solberg Woods LC. Chitre AS, et al. Among authors: gao j. Obesity (Silver Spring). 2020 Oct;28(10):1964-1973. doi: 10.1002/oby.22927. Epub 2020 Aug 29. Obesity (Silver Spring). 2020. PMID: 32860487 Free PMC article.
Genome-Wide Association Study on Three Behaviors Tested in an Open Field in Heterogeneous Stock Rats Identifies Multiple Loci Implicated in Psychiatric Disorders.
Gunturkun MH, Wang T, Chitre AS, Garcia Martinez A, Holl K, St Pierre C, Bimschleger H, Gao J, Cheng R, Polesskaya O, Solberg Woods LC, Palmer AA, Chen H. Gunturkun MH, et al. Among authors: gao j. Front Psychiatry. 2022 Feb 14;13:790566. doi: 10.3389/fpsyt.2022.790566. eCollection 2022. Front Psychiatry. 2022. PMID: 35237186 Free PMC article.
Automated quantitative trait locus analysis (AutoQTL).
Freda PJ, Ghosh A, Zhang E, Luo T, Chitre A, Polesskaya O, St Pierre CL, Gao J, Martin CD, Chen H, Garcia-Martinez AG, Wang T, Han W, Ishiwari K, Meyer P, Lamparelli A, King CP, Palmer AA, Li R, Moore JH. Freda PJ, et al. Among authors: gao j. bioRxiv [Preprint]. 2023 Jan 13:2023.01.12.523835. doi: 10.1101/2023.01.12.523835. bioRxiv. 2023. PMID: 36711526 Free PMC article. Updated. Preprint.
Genome-wide association study finds multiple loci associated with intraocular pressure in HS rats.
Fowler S, Wang T, Munro D, Kumar A, Chitre AS, Hollingsworth TJ, Garcia Martinez A, St Pierre CL, Bimschleger H, Gao J, Cheng R, Mohammadi P, Chen H, Palmer AA, Polesskaya O, Jablonski MM. Fowler S, et al. Among authors: gao j. Front Genet. 2023 Jan 30;13:1029058. doi: 10.3389/fgene.2022.1029058. eCollection 2022. Front Genet. 2023. PMID: 36793389 Free PMC article.
An exponential increase in QTL detection with an increased sample size.
Chitre AS, Polesskaya O, Munro D, Cheng R, Mohammadi P, Holl K, Gao J, Bimschleger H, Martinez AG, George AM, Gileta AF, Han W, Horvath A, Hughson A, Ishiwari K, King CP, Lamparelli A, Versaggi CL, Martin CD, St Pierre CL, Tripi JA, Richards JB, Wang T, Chen H, Flagel SB, Meyer P, Robinson TE, Solberg Woods LC, Palmer AA. Chitre AS, et al. Among authors: gao j. Genetics. 2023 May 26;224(2):iyad054. doi: 10.1093/genetics/iyad054. Genetics. 2023. PMID: 36974931 Free PMC article.
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