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FANCD2 and RAD51 recombinase directly inhibit DNA2 nuclease at stalled replication forks and FANCD2 acts as a novel RAD51 mediator in strand exchange to promote genome stability.
Nucleic Acids Res. 2023 Sep 22;51(17):9144-9165. doi: 10.1093/nar/gkad624.
Nucleic Acids Res. 2023.
PMID: 37526271
Free PMC article.
Enzymatic bypass of an N6-deoxyadenosine DNA-ethylene dibromide-peptide cross-link by translesion DNA polymerases.
Ghodke PP, Gonzalez-Vasquez G, Wang H, Johnson KM, Sedgeman CA, Guengerich FP.
Ghodke PP, et al. Among authors: sedgeman ca.
J Biol Chem. 2021 Jan-Jun;296:100444. doi: 10.1016/j.jbc.2021.100444. Epub 2021 Feb 20.
J Biol Chem. 2021.
PMID: 33617883
Free PMC article.
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Fate of triazoles in softwood upon environmental exposure.
Kukowski K, Martinská V, Sedgeman CA, Kuplic P, Kozliak EI, Fisher S, Kubátová A.
Kukowski K, et al. Among authors: sedgeman ca.
Chemosphere. 2017 Oct;184:261-268. doi: 10.1016/j.chemosphere.2017.05.168. Epub 2017 Jun 2.
Chemosphere. 2017.
PMID: 28601008
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Formation of S-[2-(N6-Deoxyadenosinyl)ethyl]glutathione in DNA and Replication Past the Adduct by Translesion DNA Polymerases.
Sedgeman CA, Su Y, Guengerich FP.
Sedgeman CA, et al.
Chem Res Toxicol. 2017 May 15;30(5):1188-1196. doi: 10.1021/acs.chemrestox.7b00022. Epub 2017 Apr 14.
Chem Res Toxicol. 2017.
PMID: 28395138
Free PMC article.
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Effects of Olive Metabolites on DNA Cleavage Mediated by Human Type II Topoisomerases.
Vann KR, Sedgeman CA, Gopas J, Golan-Goldhirsh A, Osheroff N.
Vann KR, et al. Among authors: sedgeman ca.
Biochemistry. 2015 Jul 28;54(29):4531-41. doi: 10.1021/acs.biochem.5b00162. Epub 2015 Jul 13.
Biochemistry. 2015.
PMID: 26132160
Free PMC article.
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Aromatic hydroxylation of salicylic acid and aspirin by human cytochromes P450.
Bojić M, Sedgeman CA, Nagy LD, Guengerich FP.
Bojić M, et al. Among authors: sedgeman ca.
Eur J Pharm Sci. 2015 Jun 20;73:49-56. doi: 10.1016/j.ejps.2015.03.015. Epub 2015 Mar 31.
Eur J Pharm Sci. 2015.
PMID: 25840124
Free PMC article.
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Method development for the determination of wood preservatives in commercially treated wood using gas chromatography-mass spectrometry.
Šťávová J, Sedgeman CA, Smith ZT, Frink LA, Hart JA, Niri VH, Kubátová A.
Šťávová J, et al. Among authors: sedgeman ca.
Anal Chim Acta. 2011 Sep 30;702(2):205-12. doi: 10.1016/j.aca.2011.06.058. Epub 2011 Jul 12.
Anal Chim Acta. 2011.
PMID: 21839199
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