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Deficiency in the neural cell adhesion molecule 2 (NCAM2) reduces axonal levels of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1), affects axonal organization in the hippocampus, and leads to behavioral deficits.
Cereb Cortex. 2023 Sep 9;33(18):10047-10065. doi: 10.1093/cercor/bhad264.
Cereb Cortex. 2023.
PMID: 37522285
The BACE1-generated C-terminal fragment of the neural cell adhesion molecule 2 (NCAM2) promotes BACE1 targeting to Rab11-positive endosomes.
Keable R, Hu S, Pfundstein G, Kozlova I, Su F, Du X, Yang H, Gunnersen J, Schachner M, Leshchyns'ka I, Sytnyk V.
Keable R, et al.
Cell Mol Life Sci. 2022 Oct 17;79(11):555. doi: 10.1007/s00018-022-04575-w.
Cell Mol Life Sci. 2022.
PMID: 36251052
Free PMC article.
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Cell Adhesion Molecules and Protein Synthesis Regulation in Neurons.
Kozlova I, Sah S, Keable R, Leshchyns'ka I, Janitz M, Sytnyk V.
Kozlova I, et al. Among authors: keable r.
Front Mol Neurosci. 2020 Nov 12;13:592126. doi: 10.3389/fnmol.2020.592126. eCollection 2020.
Front Mol Neurosci. 2020.
PMID: 33281551
Free PMC article.
Review.
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Trafficking and Activity of Glutamate and GABA Receptors: Regulation by Cell Adhesion Molecules.
Keable R, Leshchyns'ka I, Sytnyk V.
Keable R, et al.
Neuroscientist. 2020 Oct-Dec;26(5-6):415-437. doi: 10.1177/1073858420921117. Epub 2020 May 23.
Neuroscientist. 2020.
PMID: 32449484
Review.
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Early transcriptome changes in response to chemical long-term potentiation induced via activation of synaptic NMDA receptors in mouse hippocampal neurons.
Bliim N, Leshchyns'ka I, Keable R, Chen BJ, Curry-Hyde A, Gray L, Sytnyk V, Janitz M.
Bliim N, et al. Among authors: keable r.
Genomics. 2019 Dec;111(6):1676-1686. doi: 10.1016/j.ygeno.2018.11.019. Epub 2018 Nov 20.
Genomics. 2019.
PMID: 30465913
Free article.
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