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Illuminating the neuropeptide Y4 receptor and its ligand pancreatic polypeptide from a structural, functional, and therapeutic perspective.
Neuropeptides. 2024 Jun;105:102416. doi: 10.1016/j.npep.2024.102416. Epub 2024 Feb 24.
Neuropeptides. 2024.
PMID: 38430725
Free article.
Review.
Structure-Activity Relationship Study of the High-Affinity Neuropeptide Y4 Receptor Positive Allosteric Modulator VU0506013.
Schüß C, Vu O, Mishra NM, Tough IR, Du Y, Stichel J, Cox HM, Weaver CD, Meiler J, Emmitte KA, Beck-Sickinger AG.
Schüß C, et al.
J Med Chem. 2023 Jul 13;66(13):8745-8766. doi: 10.1021/acs.jmedchem.3c00383. Epub 2023 Jun 20.
J Med Chem. 2023.
PMID: 37339079
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Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors.
Tang T, Tan Q, Han S, Diemar A, Löbner K, Wang H, Schüß C, Behr V, Mörl K, Wang M, Chu X, Yi C, Keller M, Kofoed J, Reedtz-Runge S, Kaiser A, Beck-Sickinger AG, Zhao Q, Wu B.
Tang T, et al. Among authors: schuss c.
Sci Adv. 2022 May 6;8(18):eabm1232. doi: 10.1126/sciadv.abm1232. Epub 2022 May 4.
Sci Adv. 2022.
PMID: 35507650
Free PMC article.
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Smart mask - Wearable IoT solution for improved protection and personal health.
Hyysalo J, Dasanayake S, Hannu J, Schuss C, Rajanen M, Leppänen T, Doermann D, Sauvola J.
Hyysalo J, et al. Among authors: schuss c.
Internet Things (Amst). 2022 May;18:100511. doi: 10.1016/j.iot.2022.100511. Epub 2022 Feb 25.
Internet Things (Amst). 2022.
PMID: 37521492
Free PMC article.
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Highly Selective Y4 Receptor Antagonist Binds in an Allosteric Binding Pocket.
Schüß C, Vu O, Schubert M, Du Y, Mishra NM, Tough IR, Stichel J, Weaver CD, Emmitte KA, Cox HM, Meiler J, Beck-Sickinger AG.
Schüß C, et al.
J Med Chem. 2021 Mar 11;64(5):2801-2814. doi: 10.1021/acs.jmedchem.0c02000. Epub 2021 Feb 17.
J Med Chem. 2021.
PMID: 33595306
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