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High-content screening of drug combinations of an mPGES-1 inhibitor in multicellular tumor spheroids leads to mechanistic insights into neuroblastoma chemoresistance.
Zaghmi A, Aybay E, Jiang L, Shang M, Steinmetz-Späh J, Wermeling F, Kogner P, Korotkova M, Östling P, Jakobsson PJ, Seashore-Ludlow B, Larsson K. Zaghmi A, et al. Among authors: larsson k. Mol Oncol. 2024 Feb;18(2):317-335. doi: 10.1002/1878-0261.13502. Epub 2023 Aug 21. Mol Oncol. 2024. PMID: 37519014 Free PMC article.
MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells.
Zirath H, Frenzel A, Oliynyk G, Segerström L, Westermark UK, Larsson K, Munksgaard Persson M, Hultenby K, Lehtiö J, Einvik C, Påhlman S, Kogner P, Jakobsson PJ, Henriksson MA. Zirath H, et al. Among authors: larsson k. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10258-63. doi: 10.1073/pnas.1222404110. Epub 2013 Jun 3. Proc Natl Acad Sci U S A. 2013. PMID: 23733953 Free PMC article.
Deletion of mPGES-1 affects platelet functions in mice.
Raouf J, Mobarrez F, Larsson K, Jakobsson PJ, Korotkova M. Raouf J, et al. Among authors: larsson k. Clin Sci (Lond). 2016 Dec 1;130(24):2295-2303. doi: 10.1042/CS20160463. Epub 2016 Oct 7. Clin Sci (Lond). 2016. PMID: 27758933
1,058 results