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High-content screening of drug combinations of an mPGES-1 inhibitor in multicellular tumor spheroids leads to mechanistic insights into neuroblastoma chemoresistance.
Zaghmi A, Aybay E, Jiang L, Shang M, Steinmetz-Späh J, Wermeling F, Kogner P, Korotkova M, Östling P, Jakobsson PJ, Seashore-Ludlow B, Larsson K. Zaghmi A, et al. Among authors: jakobsson pj. Mol Oncol. 2024 Feb;18(2):317-335. doi: 10.1002/1878-0261.13502. Epub 2023 Aug 21. Mol Oncol. 2024. PMID: 37519014 Free PMC article.
Urinary prostanoids are elevated by anti-TNF and anti-IL6 receptor disease-modifying antirheumatic drugs but are not predictive of response to treatment in early rheumatoid arthritis.
Liu J, Idborg H, Korotkova M, Lend K, van Vollenhoven R, Lampa J, Rudin A, Nordström D, Gudbjornsson B, Gröndal G, Uhlig T, Hørslev-Petersen K, Lund Hetland M, Østergaard M, Nurmohamed M, Jakobsson PJ. Liu J, et al. Among authors: jakobsson pj. Arthritis Res Ther. 2024 Mar 5;26(1):61. doi: 10.1186/s13075-024-03295-9. Arthritis Res Ther. 2024. PMID: 38444034 Free PMC article. Clinical Trial.
Editorial: Insights in inflammation pharmacology: 2022.
Patrignani P, Ballerini P, Jakobsson PJ, Steinhilber D. Patrignani P, et al. Among authors: jakobsson pj. Front Pharmacol. 2023 Jun 5;14:1223761. doi: 10.3389/fphar.2023.1223761. eCollection 2023. Front Pharmacol. 2023. PMID: 37342595 Free PMC article. No abstract available.
In early rheumatoid arthritis, anticitrullinated peptide antibodies associate with low number of affected joints and rheumatoid factor associates with systemic inflammation.
Pertsinidou E, Saevarsdottir S, Manivel VA, Klareskog L, Alfredsson L, Mathsson-Alm L, Hansson M, Cornillet M, Serre G, Holmdahl R, Skriner K, Jakobsson PJ, Westerlind H, Askling J, Rönnelid J. Pertsinidou E, et al. Among authors: jakobsson pj. Ann Rheum Dis. 2024 Feb 15;83(3):277-287. doi: 10.1136/ard-2023-224728. Ann Rheum Dis. 2024. PMID: 38049984 Free PMC article.
High-mannose glycans from Schistosoma mansoni eggs are important for priming of Th2 responses via Dectin-2 and prostaglandin E2.
Almeida L, van Roey R, Patente TA, Otto F, Veldhuizen T, Ghorasaini M, van Diepen A, Schramm G, Liu J, Idborg H, Korotkova M, Jakobsson PJ, Giera M, Hokke CH, Everts B. Almeida L, et al. Among authors: jakobsson pj. Front Immunol. 2024 Apr 29;15:1372927. doi: 10.3389/fimmu.2024.1372927. eCollection 2024. Front Immunol. 2024. PMID: 38742105 Free PMC article.
Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples.
O'Donnell VB, Schebb NH, Milne GL, Murphy MP, Thomas CP, Steinhilber D, Gelhaus SL, Kühn H, Gelb MH, Jakobsson PJ, Blair IA, Murphy RC, Freeman BA, Brash AR, FitzGerald GA. O'Donnell VB, et al. Among authors: jakobsson pj. Nat Commun. 2023 Nov 9;14(1):7172. doi: 10.1038/s41467-023-41766-w. Nat Commun. 2023. PMID: 37945602 Free PMC article. No abstract available.
190 results