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EAPB0203, a member of the imidazoquinoxaline family, inhibits growth and induces caspase-dependent apoptosis in T-cell lymphomas and HTLV-I-associated adult T-cell leukemia/lymphoma.
Moarbess G, El-Hajj H, Kfoury Y, El-Sabban ME, Lepelletier Y, Hermine O, Deleuze-Masquéfa C, Bonnet PA, Bazarbachi A. Moarbess G, et al. Among authors: bonnet pa. Blood. 2008 Apr 1;111(7):3770-7. doi: 10.1182/blood-2007-11-121913. Epub 2008 Jan 24. Blood. 2008. PMID: 18218850 Free article.
New imidazoquinoxaline derivatives: Synthesis, biological evaluation on melanoma, effect on tubulin polymerization and structure-activity relationships.
Zghaib Z, Guichou JF, Vappiani J, Bec N, Hadj-Kaddour K, Vincent LA, Paniagua-Gayraud S, Larroque C, Moarbess G, Cuq P, Kassab I, Deleuze-Masquéfa C, Diab-Assaf M, Bonnet PA. Zghaib Z, et al. Among authors: bonnet pa. Bioorg Med Chem. 2016 Jun 1;24(11):2433-2440. doi: 10.1016/j.bmc.2016.04.004. Epub 2016 Apr 1. Bioorg Med Chem. 2016. PMID: 27094151
Liquid chromatography-electrospray ionization-tandem mass spectrometry method for quantitative estimation of new imiqualine leads with potent anticancer activities in rat and mouse plasma. Application to a pharmacokinetic study in mice.
Chouchou A, Marion B, Enjalbal C, Roques C, Cuq P, Bonnet PA, Bressolle-Gomeni FMM, Deleuze-Masquéfa C. Chouchou A, et al. Among authors: bonnet pa. J Pharm Biomed Anal. 2018 Jan 30;148:369-379. doi: 10.1016/j.jpba.2017.10.025. Epub 2017 Oct 24. J Pharm Biomed Anal. 2018. PMID: 29111492
Novel and Selective TLR7 Antagonists among the Imidazo[1,2-a]pyrazines, Imidazo[1,5-a]quinoxalines, and Pyrazolo[1,5-a]quinoxalines Series.
Bou Karroum N, Moarbess G, Guichou JF, Bonnet PA, Patinote C, Bouharoun-Tayoun H, Chamat S, Cuq P, Diab-Assaf M, Kassab I, Deleuze-Masquefa C. Bou Karroum N, et al. Among authors: bonnet pa. J Med Chem. 2019 Aug 8;62(15):7015-7031. doi: 10.1021/acs.jmedchem.9b00411. Epub 2019 Jul 19. J Med Chem. 2019. PMID: 31283223
86 results