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Page 1
Effects of Early Clozapine Treatment on Remission Rates in Acute Schizophrenia (The EARLY Trial): Protocol of a Randomized-Controlled Multicentric Trial.
Wagner E, Strube W, Görlitz T, Aksar A, Bauer I, Campana M, Moussiopoulou J, Hapfelmeier A, Wagner P, Egert-Schwender S, Bittner R, Eckstein K, Nenadić I, Kircher T, Langguth B, Meisenzahl E, Lambert M, Neff S, Malchow B, Falkai P, Hirjak D, Böttcher KT, Meyer-Lindenberg A, Blankenstein C, Leucht S, Hasan A. Wagner E, et al. Among authors: gorlitz t. Pharmacopsychiatry. 2023 Sep;56(5):169-181. doi: 10.1055/a-2110-4259. Epub 2023 Jul 28. Pharmacopsychiatry. 2023. PMID: 37506738 Free PMC article.
Add-on spironolactone as antagonist of the NRG1-ERBB4 signaling pathway for the treatment of schizophrenia: Study design and methodology of a multicenter randomized, placebo-controlled trial.
Hasan A, Roeh A, Leucht S, Langguth B, Hansbauer M, Oviedo-Salcedo T, Kirchner SK, Papazova I, Löhrs L, Wagner E, Maurus I, Strube W, Rossner MJ, Wehr MC, Bauer I, Heres S, Leucht C, Kreuzer PM, Zimmermann S, Schneider-Axmann T, Görlitz T, Karch S, Egert-Schwender S, Schossow B, Rothe P, Falkai P. Hasan A, et al. Among authors: gorlitz t. Contemp Clin Trials Commun. 2020 Jan 28;17:100537. doi: 10.1016/j.conctc.2020.100537. eCollection 2020 Mar. Contemp Clin Trials Commun. 2020. PMID: 32072071 Free PMC article.
Genome-wide association analyses of symptom severity among clozapine-treated patients with schizophrenia spectrum disorders.
Okhuijsen-Pfeifer C, van der Horst MZ, Bousman CA, Lin B, van Eijk KR, Ripke S, Ayhan Y, Babaoglu MO, Bak M, Alink W, van Beek H, Beld E, Bouhuis A, Edlinger M, Erdogan IM, Ertuğrul A, Yoca G, Everall IP, Görlitz T; GROUP (Genetic Risk and Outcome of Psychosis) investigators; Grootens KP, Gutwinski S, Hallikainen T, Jeger-Land E, de Koning M, Lähteenvuo M, Legge SE, Leucht S, Morgenroth C, Müderrisoğlu A, Narang A, Pantelis C, Pardiñas AF, Oviedo-Salcedo T, Schneider-Thoma J, Schreiter S, Repo-Tiihonen E, Tuppurainen H, Veereschild M, Veerman S, de Vos M, Wagner E, Cohen D, Bogers JPAM, Walters JTR, Yağcıoğlu AEA, Tiihonen J, Hasan A, Luykx JJ. Okhuijsen-Pfeifer C, et al. Among authors: gorlitz t. Transl Psychiatry. 2022 Apr 7;12(1):145. doi: 10.1038/s41398-022-01884-3. Transl Psychiatry. 2022. PMID: 35393395 Free PMC article.
Effects of add-on Celecoxib treatment on patients with schizophrenia spectrum disorders and inflammatory cytokine profile trial (TargetFlame): study design and methodology of a multicentre randomized, placebo-controlled trial.
Strube W, Aksar A, Bauer I, Barbosa S, Benros M, Blankenstein C, Campana M, Davidovic L, Glaichenhaus N, Falkai P, Görlitz T, Hansbauer M, Heilig D, Khalfallah O, Leboyer M, Martinuzzi E, Mayer S, Moussiopoulou J, Papazova I, Perić N, Wagner E, Schneider-Axmann T, Simon J, Hasan A. Strube W, et al. Among authors: gorlitz t. J Neural Transm (Vienna). 2023 Aug;130(8):1039-1048. doi: 10.1007/s00702-022-02566-6. Epub 2022 Nov 19. J Neural Transm (Vienna). 2023. PMID: 36401749 Free PMC article. Clinical Trial.
Associations Between Polygenic Risk Score Loading, Psychosis Liability, and Clozapine Use Among Individuals With Schizophrenia.
Lin BD, Pinzón-Espinosa J, Blouzard E, van der Horst MZ, Okhuijsen-Pfeifer C, van Eijk KR, Guloksuz S, Peyrot WJ, Luykx JJ; Genetic Risk and Outcome of Psychosis (GROUP) and Clozapine International Consortium (CLOZIN) Investigators. Lin BD, et al. JAMA Psychiatry. 2023 Feb 1;80(2):181-185. doi: 10.1001/jamapsychiatry.2022.4234. JAMA Psychiatry. 2023. PMID: 36542388 Free PMC article.