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Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques.
Viox EG, Hoang TN, Upadhyay AA, Nchioua R, Hirschenberger M, Strongin Z, Tharp GK, Pino M, Nguyen K, Harper JL, Gagne M, Marciano S, Boddapati AK, Pellegrini KL, Pradhan A, Tisoncik-Go J, Whitmore LS, Karunakaran KA, Roy M, Kirejczyk S, Curran EH, Wallace C, Wood JS, Connor-Stroud F, Voigt EA, Monaco CM, Gordon DE, Kasturi SP, Levit RD, Gale M Jr, Vanderford TH, Silvestri G, Busman-Sahay K, Estes JD, Vaccari M, Douek DC, Sparrer KMJ, Johnson RP, Kirchhoff F, Schreiber G, Bosinger SE, Paiardini M. Viox EG, et al. Among authors: nchioua r. Sci Immunol. 2023 Jul 28;8(85):eadg0033. doi: 10.1126/sciimmunol.adg0033. Epub 2023 Jul 28. Sci Immunol. 2023. PMID: 37506197 Free PMC article.
Reduced replication but increased interferon resistance of SARS-CoV-2 Omicron BA.1.
Nchioua R, Schundner A, Klute S, Koepke L, Hirschenberger M, Noettger S, Fois G, Zech F, Graf A, Krebs S, Braubach P, Blum H, Stenger S, Kmiec D, Frick M, Kirchhoff F, Sparrer KM. Nchioua R, et al. Life Sci Alliance. 2023 Mar 28;6(6):e202201745. doi: 10.26508/lsa.202201745. Print 2023 Jun. Life Sci Alliance. 2023. PMID: 36977594 Free PMC article.
Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques.
Hoang TN, Viox EG, Upadhyay AA, Strongin Z, Tharp GK, Pino M, Nchioua R, Hirschenberger M, Gagne M, Nguyen K, Harper JL, Marciano S, Boddapati AK, Pellegrini KL, Tisoncik-Go J, Whitmore LS, Karunakaran KA, Roy M, Kirejczyk S, Curran EH, Wallace C, Wood JS, Connor-Stroud F, Kasturi SP, Levit RD, Gale M Jr, Vanderford TH, Silvestri G, Busman-Sahay K, Estes JD, Vaccari M, Douek DC, Sparrer KMJ, Kirchhoff F, Johnson RP, Schreiber G, Bosinger SE, Paiardini M. Hoang TN, et al. Among authors: nchioua r. bioRxiv [Preprint]. 2022 Oct 24:2022.10.21.512606. doi: 10.1101/2022.10.21.512606. bioRxiv. 2022. PMID: 36324810 Free PMC article. Updated. Preprint.
Actin cytoskeleton remodeling primes RIG-I-like receptor activation.
Acharya D, Reis R, Volcic M, Liu G, Wang MK, Chia BS, Nchioua R, Groß R, Münch J, Kirchhoff F, Sparrer KMJ, Gack MU. Acharya D, et al. Among authors: nchioua r. Cell. 2022 Sep 15;185(19):3588-3602.e21. doi: 10.1016/j.cell.2022.08.011. Cell. 2022. PMID: 36113429 Free PMC article.
Serially passaged, conditionally reprogrammed nasal epithelial cells as a model to study epithelial functions and SARS-CoV-2 infection.
Schmidt H, Guthjahr L, Sauter A, Zech F, Nchioua R, Stenger S, Frick M, Kirchhoff F, Dietl P, Wittekindt OH. Schmidt H, et al. Among authors: nchioua r. Am J Physiol Cell Physiol. 2022 Apr 1;322(4):C591-C604. doi: 10.1152/ajpcell.00363.2021. Epub 2022 Feb 23. Am J Physiol Cell Physiol. 2022. PMID: 35196166 Free PMC article.
18 results