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Page 1
Spatial genomic, biochemical and cellular mechanisms underlying meningioma heterogeneity and evolution.
Lucas CG, Mirchia K, Seo K, Najem H, Chen WC, Zakimi N, Foster K, Eaton CD, Cady MA, Choudhury A, Liu SJ, Phillips JJ, Magill ST, Horbinski CM, Solomon DA, Perry A, Vasudevan HN, Heimberger AB, Raleigh DR. Lucas CG, et al. Among authors: najem h. Nat Genet. 2024 May 17. doi: 10.1038/s41588-024-01747-1. Online ahead of print. Nat Genet. 2024. PMID: 38760638
Perivascular NOTCH3+ stem cells drive meningioma tumorigenesis and resistance to radiotherapy.
Choudhury A, Cady MA, Lucas CG, Najem H, Phillips JJ, Palikuqi B, Zakimi N, Joseph T, Birrueta JO, Chen WC, Oberheim Bush NA, Hervey-Jumper SL, Klein OD, Toedebusch CM, Horbinski CM, Magill ST, Bhaduri A, Perry A, Dickinson PJ, Heimberger AB, Ashworth A, Crouch EE, Raleigh DR. Choudhury A, et al. Among authors: najem h. Cancer Discov. 2024 May 14. doi: 10.1158/2159-8290.CD-23-1459. Online ahead of print. Cancer Discov. 2024. PMID: 38742767
Prohibitin Expression in Antigen-Presenting Cells: Implications for Inciting Trigger in CNS IgG4-Related Disease.
Najem H, Arrieta VA, Duffy J, Tripathi S, Zannikou M, Dhiantravan S, Miska J, McCortney K, Steffens A, Walshon J, Lee Chang C, Dahdaleh NS, Sonabend AM, Smith Z, Horbinski CM, Chandler J, Heimberger AB, Balyasnikova IV. Najem H, et al. Ann Case Rep. 2024;9(1):1607. doi: 10.29011/2574-7754.101607. Epub 2024 Jan 25. Ann Case Rep. 2024. PMID: 38606301 Free PMC article.
Cancer-associated fibroblast-secreted collagen is associated with immune inhibitor receptor LAIR1 in gliomas.
Tripathi S, Najem H, Dussold C, Pacheco S, Miska J, McCortney K, Steffens A, Walshon J, Winkowski D, Cloney M, Ordon M, Gibson W, Kemeny H, Youngblood M, Du R, Mossner J, Texakalidis P, Sprau A, Tate M, James CD, Horbinski CM, Wadhwani NR, Lesniak MS, Lam S, Sati A, Aghi M, DeCuypere M, Heimberger AB. Tripathi S, et al. Among authors: najem h. J Clin Invest. 2024 Feb 15;134(4):e176613. doi: 10.1172/JCI176613. J Clin Invest. 2024. PMID: 38357919 Free PMC article. No abstract available.
Antigen-presenting B cells promote TCF-1+ PD1- stem-like CD8+ T-cell proliferation in glioblastoma.
Hou D, Wan H, Katz JL, Wang S, Castro BA, Vazquez-Cervantes GI, Arrieta VA, Dhiantravan S, Najem H, Rashidi A, Chia TY, Arjmandi T, Collado J, Billingham L, Lopez-Rosas A, Han Y, Sonabend AM, Heimberger AB, Zhang P, Miska J, Lee-Chang C. Hou D, et al. Among authors: najem h. Front Immunol. 2024 Jan 10;14:1295218. doi: 10.3389/fimmu.2023.1295218. eCollection 2023. Front Immunol. 2024. PMID: 38268923 Free PMC article.
Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas.
Youngblood MW, Erson-Omay Z, Li C, Najem H, Coșkun S, Tyrtova E, Montejo JD, Miyagishima DF, Barak T, Nishimura S, Harmancı AS, Clark VE, Duran D, Huttner A, Avşar T, Bayri Y, Schramm J, Boetto J, Peyre M, Riche M, Goldbrunner R, Amankulor N, Louvi A, Bilgüvar K, Pamir MN, Özduman K, Kilic T, Knight JR, Simon M, Horbinski C, Kalamarides M, Timmer M, Heimberger AB, Mishra-Gorur K, Moliterno J, Yasuno K, Günel M. Youngblood MW, et al. Among authors: najem h. Nat Commun. 2023 Oct 7;14(1):6279. doi: 10.1038/s41467-023-41926-y. Nat Commun. 2023. PMID: 37805627 Free PMC article.
The Use of Targeted Cytokines as Cancer Therapeutics in Glioblastoma.
Sooreshjani M, Tripathi S, Dussold C, Najem H, de Groot J, Lukas RV, Heimberger AB. Sooreshjani M, et al. Among authors: najem h. Cancers (Basel). 2023 Jul 23;15(14):3739. doi: 10.3390/cancers15143739. Cancers (Basel). 2023. PMID: 37509400 Free PMC article. Review.
NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy.
Choudhury A, Cady MA, Lucas CG, Najem H, Phillips JJ, Palikuqi B, Zakimi N, Joseph T, Birrueta JO, Chen WC, Bush NAO, Hervey-Jumper SL, Klein OD, Toedebusch CM, Horbinski CM, Magill ST, Bhaduri A, Perry A, Dickinson PJ, Heimberger AB, Ashworth A, Crouch EE, Raleigh DR. Choudhury A, et al. Among authors: najem h. bioRxiv [Preprint]. 2023 Jul 11:2023.07.10.548456. doi: 10.1101/2023.07.10.548456. bioRxiv. 2023. PMID: 37503127 Free PMC article. Preprint.
24 results