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Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro.
Dolan MJ, Therrien M, Jereb S, Kamath T, Gazestani V, Atkeson T, Marsh SE, Goeva A, Lojek NM, Murphy S, White CM, Joung J, Liu B, Limone F, Eggan K, Hacohen N, Bernstein BE, Glass CK, Leinonen V, Blurton-Jones M, Zhang F, Epstein CB, Macosko EZ, Stevens B. Dolan MJ, et al. Among authors: eggan k. Nat Immunol. 2023 Aug;24(8):1382-1390. doi: 10.1038/s41590-023-01558-2. Epub 2023 Jul 27. Nat Immunol. 2023. PMID: 37500887 Free PMC article.
The best of times, the worst of times for psychiatric disease.
Karayiorgou M, Flint J, Gogos JA, Malenka RC; Genetic and Neural Complexity in Psychiatry 2011 Working Group. Karayiorgou M, et al. Nat Neurosci. 2012 May 25;15(6):811-2. doi: 10.1038/nn.3115. Nat Neurosci. 2012. PMID: 22627793 Free PMC article.
Impracticality of egg donor recruitment in the absence of compensation.
Egli D, Chen AE, Saphier G, Powers D, Alper M, Katz K, Berger B, Goland R, Leibel RL, Melton DA, Eggan K. Egli D, et al. Among authors: eggan k. Cell Stem Cell. 2011 Oct 4;9(4):293-4. doi: 10.1016/j.stem.2011.08.002. Cell Stem Cell. 2011. PMID: 21982228 Free article. No abstract available.
A functionally characterized test set of human induced pluripotent stem cells.
Boulting GL, Kiskinis E, Croft GF, Amoroso MW, Oakley DH, Wainger BJ, Williams DJ, Kahler DJ, Yamaki M, Davidow L, Rodolfa CT, Dimos JT, Mikkilineni S, MacDermott AB, Woolf CJ, Henderson CE, Wichterle H, Eggan K. Boulting GL, et al. Among authors: eggan k. Nat Biotechnol. 2011 Mar;29(3):279-86. doi: 10.1038/nbt.1783. Epub 2011 Feb 3. Nat Biotechnol. 2011. PMID: 21293464 Free PMC article.
Somatic coding mutations in human induced pluripotent stem cells.
Gore A, Li Z, Fung HL, Young JE, Agarwal S, Antosiewicz-Bourget J, Canto I, Giorgetti A, Israel MA, Kiskinis E, Lee JH, Loh YH, Manos PD, Montserrat N, Panopoulos AD, Ruiz S, Wilbert ML, Yu J, Kirkness EF, Izpisua Belmonte JC, Rossi DJ, Thomson JA, Eggan K, Daley GQ, Goldstein LS, Zhang K. Gore A, et al. Among authors: eggan k. Nature. 2011 Mar 3;471(7336):63-7. doi: 10.1038/nature09805. Nature. 2011. PMID: 21368825 Free PMC article.
DNA methylation dynamics of the human preimplantation embryo.
Smith ZD, Chan MM, Humm KC, Karnik R, Mekhoubad S, Regev A, Eggan K, Meissner A. Smith ZD, et al. Among authors: eggan k. Nature. 2014 Jul 31;511(7511):611-5. doi: 10.1038/nature13581. Epub 2014 Jul 23. Nature. 2014. PMID: 25079558 Free PMC article.
Automated, high-throughput derivation, characterization and differentiation of induced pluripotent stem cells.
Paull D, Sevilla A, Zhou H, Hahn AK, Kim H, Napolitano C, Tsankov A, Shang L, Krumholz K, Jagadeesan P, Woodard CM, Sun B, Vilboux T, Zimmer M, Forero E, Moroziewicz DN, Martinez H, Malicdan MC, Weiss KA, Vensand LB, Dusenberry CR, Polus H, Sy KT, Kahler DJ, Gahl WA, Solomon SL, Chang S, Meissner A, Eggan K, Noggle SA. Paull D, et al. Among authors: eggan k. Nat Methods. 2015 Sep;12(9):885-92. doi: 10.1038/nmeth.3507. Epub 2015 Aug 3. Nat Methods. 2015. PMID: 26237226
Modeling ALS with motor neurons derived from human induced pluripotent stem cells.
Sances S, Bruijn LI, Chandran S, Eggan K, Ho R, Klim JR, Livesey MR, Lowry E, Macklis JD, Rushton D, Sadegh C, Sareen D, Wichterle H, Zhang SC, Svendsen CN. Sances S, et al. Among authors: eggan k. Nat Neurosci. 2016 Apr;19(4):542-53. doi: 10.1038/nn.4273. Nat Neurosci. 2016. PMID: 27021939 Free PMC article. Review.
162 results