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Virtual screening and biological evaluation to identify pharmaceuticals potentially causing hypertension and hypokalemia by inhibiting steroid 11β-hydroxylase.
Jäger MC, Kędzierski J, Gell V, Wey T, Kollár J, Winter DV, Schuster D, Smieško M, Odermatt A. Jäger MC, et al. Among authors: schuster d. Toxicol Appl Pharmacol. 2023 Sep 15;475:116638. doi: 10.1016/j.taap.2023.116638. Epub 2023 Jul 26. Toxicol Appl Pharmacol. 2023. PMID: 37499767 Free article.
Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11β-hydroxylase and aldosterone synthase.
Akram M, Patt M, Kaserer T, Temml V, Waratchareeyakul W, Kratschmar DV, Haupenthal J, Hartmann RW, Odermatt A, Schuster D. Akram M, et al. Among authors: schuster d. J Steroid Biochem Mol Biol. 2019 Sep;192:105358. doi: 10.1016/j.jsbmb.2019.04.007. Epub 2019 Apr 6. J Steroid Biochem Mol Biol. 2019. PMID: 30965118
893 results