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Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering.
Li L, Mohanty V, Dou J, Huang Y, Banerjee PP, Miao Q, Lohr JG, Vijaykumar T, Frede J, Knoechel B, Muniz-Feliciano L, Laskowski TJ, Liang S, Moyes JS, Nandivada V, Basar R, Kaplan M, Daher M, Liu E, Li Y, Acharya S, Lin P, Shanley M, Rafei H, Marin D, Mielke S, Champlin RE, Shpall EJ, Chen K, Rezvani K. Li L, et al. Among authors: lohr jg. Sci Adv. 2023 Jul 28;9(30):eadd6997. doi: 10.1126/sciadv.add6997. Epub 2023 Jul 26. Sci Adv. 2023. PMID: 37494448 Free PMC article.
Role of B7 in T cell tolerance.
Lohr J, Knoechel B, Kahn EC, Abbas AK. Lohr J, et al. J Immunol. 2004 Oct 15;173(8):5028-35. doi: 10.4049/jimmunol.173.8.5028. J Immunol. 2004. PMID: 15470046
Regulatory T cells in the periphery.
Lohr J, Knoechel B, Abbas AK. Lohr J, et al. Immunol Rev. 2006 Aug;212:149-62. doi: 10.1111/j.0105-2896.2006.00414.x. Immunol Rev. 2006. PMID: 16903912 Review.
Balancing autoaggressive and protective T cell responses.
Abbas AK, Lohr J, Knoechel B. Abbas AK, et al. J Autoimmun. 2007 Mar-May;28(2-3):59-61. doi: 10.1016/j.jaut.2007.02.002. Epub 2007 Mar 23. J Autoimmun. 2007. PMID: 17363216 Free PMC article. Review.
An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
Knoechel B, Roderick JE, Williamson KE, Zhu J, Lohr JG, Cotton MJ, Gillespie SM, Fernandez D, Ku M, Wang H, Piccioni F, Silver SJ, Jain M, Pearson D, Kluk MJ, Ott CJ, Shultz LD, Brehm MA, Greiner DL, Gutierrez A, Stegmaier K, Kung AL, Root DE, Bradner JE, Aster JC, Kelliher MA, Bernstein BE. Knoechel B, et al. Among authors: lohr jg. Nat Genet. 2014 Apr;46(4):364-70. doi: 10.1038/ng.2913. Epub 2014 Mar 2. Nat Genet. 2014. PMID: 24584072 Free PMC article.
Genomic discovery and clonal tracking in multiple myeloma by cell-free DNA sequencing.
Guo G, Raje NS, Seifer C, Kloeber J, Isenhart R, Ha G, Yee AJ, O'Donnell EK, Tai YT, Richardson PG, Bianchi G, Laubach JP, Warren D, Gemme E, Voisine J, Frede J, Kokkalis A, Yun H, Dimitrova V, Vijaykumar T, Meyerson M, Munshi NC, Anderson KC, Knoechel B, Lohr JG. Guo G, et al. Among authors: lohr jg. Leukemia. 2018 Aug;32(8):1838-1841. doi: 10.1038/s41375-018-0115-z. Epub 2018 Mar 27. Leukemia. 2018. PMID: 29749395 Free PMC article. Clinical Trial. No abstract available.
38 results