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Page 1
Intestinal microbiota controls graft-versus-host disease independent of donor-host genetic disparity.
Koyama M, Hippe DS, Srinivasan S, Proll SC, Miltiadous O, Li N, Zhang P, Ensbey KS, Hoffman NG, Schmidt CR, Yeh AC, Minnie SA, Strenk SM, Fiedler TL, Hattangady N, Kowalsky J, Grady WM, Degli-Esposti MA, Varelias A, Clouston AD, van den Brink MRM, Dey N, Randolph TW, Markey KA, Fredricks DN, Hill GR. Koyama M, et al. Among authors: van den brink mrm. Immunity. 2023 Aug 8;56(8):1876-1893.e8. doi: 10.1016/j.immuni.2023.06.024. Epub 2023 Jul 21. Immunity. 2023. PMID: 37480848
Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease.
Hanash AM, Dudakov JA, Hua G, O'Connor MH, Young LF, Singer NV, West ML, Jenq RR, Holland AM, Kappel LW, Ghosh A, Tsai JJ, Rao UK, Yim NL, Smith OM, Velardi E, Hawryluk EB, Murphy GF, Liu C, Fouser LA, Kolesnick R, Blazar BR, van den Brink MR. Hanash AM, et al. Immunity. 2012 Aug 24;37(2):339-50. doi: 10.1016/j.immuni.2012.05.028. Immunity. 2012. PMID: 22921121 Free PMC article.
Autophagy gene Atg16L1 prevents lethal T cell alloreactivity mediated by dendritic cells.
Hubbard-Lucey VM, Shono Y, Maurer K, West ML, Singer NV, Ziegler CG, Lezcano C, Motta AC, Schmid K, Levi SM, Murphy GF, Liu C, Winkler JD, Amaravadi RK, Rogler G, Dickinson AM, Holler E, van den Brink MR, Cadwell K. Hubbard-Lucey VM, et al. Immunity. 2014 Oct 16;41(4):579-91. doi: 10.1016/j.immuni.2014.09.011. Epub 2014 Oct 9. Immunity. 2014. PMID: 25308334 Free PMC article.
Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality.
Saha A, Taylor PA, Lees CJ, Panoskaltsis-Mortari A, Osborn MJ, Feser CJ, Thangavelu G, Melchinger W, Refaeli Y, Hill GR, Munn DH, Murphy WJ, Serody JS, Maillard I, Kreymborg K, van den Brink M, Dong C, Huang S, Zang X, Allison JP, Zeiser R, Blazar BR. Saha A, et al. JCI Insight. 2019 Oct 3;4(19):e127716. doi: 10.1172/jci.insight.127716. JCI Insight. 2019. PMID: 31578305 Free PMC article.
Lactose drives Enterococcus expansion to promote graft-versus-host disease.
Stein-Thoeringer CK, Nichols KB, Lazrak A, Docampo MD, Slingerland AE, Slingerland JB, Clurman AG, Armijo G, Gomes ALC, Shono Y, Staffas A, Burgos da Silva M, Devlin SM, Markey KA, Bajic D, Pinedo R, Tsakmaklis A, Littmann ER, Pastore A, Taur Y, Monette S, Arcila ME, Pickard AJ, Maloy M, Wright RJ, Amoretti LA, Fontana E, Pham D, Jamal MA, Weber D, Sung AD, Hashimoto D, Scheid C, Xavier JB, Messina JA, Romero K, Lew M, Bush A, Bohannon L, Hayasaka K, Hasegawa Y, Vehreschild MJGT, Cross JR, Ponce DM, Perales MA, Giralt SA, Jenq RR, Teshima T, Holler E, Chao NJ, Pamer EG, Peled JU, van den Brink MRM. Stein-Thoeringer CK, et al. Among authors: van den brink mrm. Science. 2019 Nov 29;366(6469):1143-1149. doi: 10.1126/science.aax3760. Science. 2019. PMID: 31780560 Free PMC article.
270 results