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A Phase 2 randomised study to establish efficacy, safety and dosing of a novel oral cathepsin C inhibitor, BI 1291583, in adults with bronchiectasis: Airleaf.
Chalmers JD, Gupta A, Chotirmall SH, Armstrong A, Eickholz P, Hasegawa N, McShane PJ, O'Donnell AE, Shteinberg M, Watz H, Eleftheraki A, Diefenbach C, Sauter W. Chalmers JD, et al. Among authors: chotirmall sh. ERJ Open Res. 2023 Jun 26;9(3):00633-2022. doi: 10.1183/23120541.00633-2022. eCollection 2023 May. ERJ Open Res. 2023. PMID: 37465817 Free PMC article.
RESPIRE: breathing new life into bronchiectasis.
Chotirmall SH, Chalmers JD. Chotirmall SH, et al. Eur Respir J. 2018 Jan 25;51(1):1702444. doi: 10.1183/13993003.02444-2017. Print 2018 Jan. Eur Respir J. 2018. PMID: 29371393 Free article. No abstract available.
Bronchiectasis: new therapies and new perspectives.
Chalmers JD, Chotirmall SH. Chalmers JD, et al. Among authors: chotirmall sh. Lancet Respir Med. 2018 Sep;6(9):715-726. doi: 10.1016/S2213-2600(18)30053-5. Epub 2018 Feb 23. Lancet Respir Med. 2018. PMID: 29478908
Bronchiectasis: an emerging global epidemic.
Chotirmall SH, Chalmers JD. Chotirmall SH, et al. BMC Pulm Med. 2018 May 22;18(1):76. doi: 10.1186/s12890-018-0629-1. BMC Pulm Med. 2018. PMID: 29788944 Free PMC article.
Immunological corollary of the pulmonary mycobiome in bronchiectasis: the CAMEB study.
Mac Aogáin M, Chandrasekaran R, Lim AYH, Low TB, Tan GL, Hassan T, Ong TH, Hui Qi Ng A, Bertrand D, Koh JY, Pang SL, Lee ZY, Gwee XW, Martinus C, Sio YY, Matta SA, Chew FT, Keir HR, Connolly JE, Abisheganaden JA, Koh MS, Nagarajan N, Chalmers JD, Chotirmall SH. Mac Aogáin M, et al. Among authors: chotirmall sh. Eur Respir J. 2018 Jul 27;52(1):1800766. doi: 10.1183/13993003.00766-2018. Print 2018 Jul. Eur Respir J. 2018. PMID: 29880655 Free PMC article.
Distinct "Immunoallertypes" of Disease and High Frequencies of Sensitization in Non-Cystic Fibrosis Bronchiectasis.
Mac Aogáin M, Tiew PY, Lim AYH, Low TB, Tan GL, Hassan T, Ong TH, Pang SL, Lee ZY, Gwee XW, Martinus C, Sio YY, Matta SA, Ong TC, Tiong YS, Wong KN, Narayanan S, Au VB, Marlier D, Keir HR, Tee A, Abisheganaden JA, Koh MS, Wang Y, Connolly JE, Chew FT, Chalmers JD, Chotirmall SH. Mac Aogáin M, et al. Among authors: chotirmall sh. Am J Respir Crit Care Med. 2019 Apr 1;199(7):842-853. doi: 10.1164/rccm.201807-1355OC. Am J Respir Crit Care Med. 2019. PMID: 30265843
Bronchiectasis.
Chalmers JD, Chang AB, Chotirmall SH, Dhar R, McShane PJ. Chalmers JD, et al. Among authors: chotirmall sh. Nat Rev Dis Primers. 2018 Nov 15;4(1):45. doi: 10.1038/s41572-018-0042-3. Nat Rev Dis Primers. 2018. PMID: 30442957 Review.
Increased Chitotriosidase Is Associated With Aspergillus and Frequent Exacerbations in South-East Asian Patients With Bronchiectasis.
Poh TY, Tiew PY, Lim AYH, Thng KX, Binte Mohamed Ali NA, Narayana JK, Mac Aogáin M, Tien Z, Chew WM, Wai Chan AK, Keir HR, Dicker AJ, Hassan TM, Xu H, Tee AKH, Ong TH, Koh MS, Abisheganaden JA, Chalmers JD, Chotirmall SH. Poh TY, et al. Among authors: chotirmall sh. Chest. 2020 Aug;158(2):512-522. doi: 10.1016/j.chest.2020.02.048. Epub 2020 Mar 14. Chest. 2020. PMID: 32184111
179 results