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Mycobacterium tuberculosis PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas.
Ottavi S, Li K, Cacioppo JG, Perkowski AJ, Ramesh R, Gold BS, Ling Y, Roberts J, Singh A, Zhang D, Mosior J, Goullieux L, Roubert C, Bacqué E, Sacchettini JC, Nathan CF, Aubé J. Ottavi S, et al. Among authors: aube j. ACS Med Chem Lett. 2023 Jun 26;14(7):970-976. doi: 10.1021/acsmedchemlett.3c00162. eCollection 2023 Jul 13. ACS Med Chem Lett. 2023. PMID: 37465309
Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis.
Gold B, Smith R, Nguyen Q, Roberts J, Ling Y, Lopez Quezada L, Somersan S, Warrier T, Little D, Pingle M, Zhang D, Ballinger E, Zimmerman M, Dartois V, Hanson P, Mitscher LA, Porubsky P, Rogers S, Schoenen FJ, Nathan C, Aubé J. Gold B, et al. Among authors: aube j. J Med Chem. 2016 Jul 14;59(13):6027-44. doi: 10.1021/acs.jmedchem.5b01833. Epub 2016 Jun 17. J Med Chem. 2016. PMID: 27144688 Free PMC article.
The Ex Vivo Treatment of Donor T Cells with Cosalane, an HIV Therapeutic and Small-Molecule Antagonist of CC-Chemokine Receptor 7, Separates Acute Graft-versus-Host Disease from Graft-versus-Leukemia Responses in Murine Hematopoietic Stem Cell Transplantation Models.
Fowler KA, Li K, Whitehurst CB, Bruce DW, Moorman NJ, Aubé J, Coghill JM. Fowler KA, et al. Among authors: aube j. Biol Blood Marrow Transplant. 2019 Jun;25(6):1062-1074. doi: 10.1016/j.bbmt.2019.01.022. Epub 2019 Jan 19. Biol Blood Marrow Transplant. 2019. PMID: 30668984 Free article.
Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition.
Ballinger E, Mosior J, Hartman T, Burns-Huang K, Gold B, Morris R, Goullieux L, Blanc I, Vaubourgeix J, Lagrange S, Fraisse L, Sans S, Couturier C, Bacqué E, Rhee K, Scarry SM, Aubé J, Yang G, Ouerfelli O, Schnappinger D, Ioerger TR, Engelhart CA, McConnell JA, McAulay K, Fay A, Roubert C, Sacchettini J, Nathan C. Ballinger E, et al. Among authors: aube j. Science. 2019 Feb 1;363(6426):eaau8959. doi: 10.1126/science.aau8959. Science. 2019. PMID: 30705156 Free PMC article.
278 results