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Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation.
Mooser C, Symeonidou IE, Leimbacher PA, Ribeiro A, Shorrocks AK, Jungmichel S, Larsen SC, Knechtle K, Jasrotia A, Zurbriggen D, Jeanrenaud A, Leikauf C, Fink D, Nielsen ML, Blackford AN, Stucki M. Mooser C, et al. Among authors: nielsen ml. Nat Commun. 2020 Jan 8;11(1):123. doi: 10.1038/s41467-019-13981-x. Nat Commun. 2020. PMID: 31913317 Free PMC article.
Serine-linked PARP1 auto-modification controls PARP inhibitor response.
Prokhorova E, Zobel F, Smith R, Zentout S, Gibbs-Seymour I, Schützenhofer K, Peters A, Groslambert J, Zorzini V, Agnew T, Brognard J, Nielsen ML, Ahel D, Huet S, Suskiewicz MJ, Ahel I. Prokhorova E, et al. Among authors: nielsen ml. Nat Commun. 2021 Jul 1;12(1):4055. doi: 10.1038/s41467-021-24361-9. Nat Commun. 2021. PMID: 34210965 Free PMC article.
The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome.
Hendriks IA, Buch-Larsen SC, Prokhorova E, Elsborg JD, Rebak AKLFS, Zhu K, Ahel D, Lukas C, Ahel I, Nielsen ML. Hendriks IA, et al. Among authors: nielsen ml. Nat Commun. 2021 Oct 8;12(1):5893. doi: 10.1038/s41467-021-26172-4. Nat Commun. 2021. PMID: 34625544 Free PMC article.
342 results