Mukhaleva E - Search Results

1

Bayesian network models identify cooperative GPCR:G protein interactions that contribute to G protein coupling.

Mukhaleva E, Ma N, van der Velden WJC, Gogoshin G, Branciamore S, Bhattacharya S, Rodin AS, Vaidehi N. Mukhaleva E, et al. J Biol Chem. 2024 May 10:107362. doi: 10.1016/j.jbc.2024.107362. Online ahead of print. J Biol Chem. 2024. PMID: 38735478 Free article.

2

Stabilization of interdomain interactions in G protein α subunits as a determinant of Gα_i subtype signaling specificity.

Lefevre TJ, Wei W, Mukhaleva E, Meda Venkata SP, Chandan NR, Abraham S, Li Y, Dessauer CW, Vaidehi N, Smrcka AV. Lefevre TJ, et al. Among authors: mukhaleva e. J Biol Chem. 2024 Mar 22;300(5):107211. doi: 10.1016/j.jbc.2024.107211. Online ahead of print. J Biol Chem. 2024. PMID: 38522511 Free PMC article.

3

Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery.

Chan AKN, Han L, Delaney CD, Wang X, Mukhaleva E, Li M, Yang L, Pokharel SP, Mattson N, Garcia M, Wang B, Xu X, Zhang L, Singh P, Elsayed Z, Chen R, Kuang B, Wang J, Yuan YC, Chen B, Chan LN, Rosen ST, Horne D, Müschen M, Chen J, Vaidehi N, Armstrong SA, Su R, Chen CW. Chan AKN, et al. Among authors: mukhaleva e. Sci Adv. 2024 Feb 23;10(8):eadk3127. doi: 10.1126/sciadv.adk3127. Epub 2024 Feb 23. Sci Adv. 2024. PMID: 38394203 Free PMC article.

4

A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens.

Mattson NM, Chan AKN, Miyashita K, Mukhaleva E, Chang WH, Yang L, Ma N, Wang Y, Pokharel SP, Li M, Liu Q, Xu X, Chen R, Singh P, Zhang L, Elsayed Z, Chen B, Keen D, Pirrotte P, Rosen ST, Chen J, LaBarge MA, Shively JE, Vaidehi N, Rockne RC, Feng M, Chen CW. Mattson NM, et al. Among authors: mukhaleva e. Nat Struct Mol Biol. 2024 Mar;31(3):465-475. doi: 10.1038/s41594-024-01211-y. Epub 2024 Feb 5. Nat Struct Mol Biol. 2024. PMID: 38316881 Free PMC article.

5

Cellular Lipids Regulate the Conformational Ensembles of the Disordered Intracellular Loop 3 in β2 Adrenergic Receptor.

Mukhaleva E, Yang T, Sadler F, Sivaramakrishnan S, Ma N, Vaidehi N. Mukhaleva E, et al. bioRxiv [Preprint]. 2023 Nov 29:2023.11.28.569080. doi: 10.1101/2023.11.28.569080. bioRxiv. 2023. PMID: 38077083 Free PMC article. Preprint.

6

Bayesian network models identify co-operative GPCR:G protein interactions that contribute to G protein coupling.

Mukhaleva E, Ma N, van der Velden WJC, Gogoshin G, Branciamore S, Bhattacharya S, Rodin AS, Vaidehi N. Mukhaleva E, et al. bioRxiv [Preprint]. 2023 Oct 12:2023.10.09.561618. doi: 10.1101/2023.10.09.561618. bioRxiv. 2023. PMID: 37873104 Free PMC article. Updated. Preprint.

7

Molecular recognition of an aversive odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Verprintsev DB, Vaidehi N, Weyand SN, Tate CG. Gusach A, et al. Among authors: mukhaleva e. bioRxiv [Preprint]. 2023 Jul 7:2023.07.07.547762. doi: 10.1101/2023.07.07.547762. bioRxiv. 2023. PMID: 37461561 Free PMC article. Preprint.

8

Stabilization of Interdomain Interactions in G protein α_i Subunits Determines Gα_i Subtype Signaling Specificity.

Lefevre TJ, Wei W, Mukhaleva E, Venkata SPM, Chandan NR, Abraham S, Li Y, Dessauer CW, Vaidehi N, Smrcka AV. Lefevre TJ, et al. Among authors: mukhaleva e. bioRxiv [Preprint]. 2023 Apr 6:2023.03.10.532072. doi: 10.1101/2023.03.10.532072. bioRxiv. 2023. PMID: 37066214 Free PMC article. Updated. Preprint.

9

Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity.

Sandhu M, Cho A, Ma N, Mukhaleva E, Namkung Y, Lee S, Ghosh S, Lee JH, Gloriam DE, Laporte SA, Babu MM, Vaidehi N. Sandhu M, et al. Among authors: mukhaleva e. Nat Commun. 2022 Dec 2;13(1):7428. doi: 10.1038/s41467-022-34055-5. Nat Commun. 2022. PMID: 36460632 Free PMC article.

10

Neuroprotective Effects of Methylene Blue In Vivo and In Vitro.

Stelmashook EV, Genrikhs EE, Mukhaleva EV, Kapkaeva MR, Kondratenko RV, Skrebitsky VG, Isaev NK. Stelmashook EV, et al. Among authors: mukhaleva ev. Bull Exp Biol Med. 2019 Aug;167(4):455-459. doi: 10.1007/s10517-019-04548-3. Epub 2019 Sep 6. Bull Exp Biol Med. 2019. PMID: 31493258

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