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Discovery of 4-benzyloxy and 4-(2-phenylethoxy) chalcone fibrate hybrids as novel PPARα agonists with anti-hyperlipidemic and antioxidant activities: Design, synthesis and in vitro/in vivo biological evaluation.
Hassan RM, Aboutabl ME, Bozzi M, El-Behairy MF, El Kerdawy AM, Sampaolese B, Desiderio C, Vincenzoni F, Sciandra F, Ghannam IAY. Hassan RM, et al. Bioorg Chem. 2021 Oct;115:105170. doi: 10.1016/j.bioorg.2021.105170. Epub 2021 Jul 16. Bioorg Chem. 2021. PMID: 34332233
Design and synthesis of novel rigid dibenzo[b,f]azepines through ring closure technique as promising anticancer candidates against leukaemia and acting as selective topoisomerase II inhibitors and DNA intercalators.
El-Behairy MF, Abd-Allah WH, Khalifa MM, Nafie MS, Saleh MA, Abdel-Maksoud MS, Al-Warhi T, Eldehna WM, Al-Karmalawy AA. El-Behairy MF, et al. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2157825. doi: 10.1080/14756366.2022.2157825. J Enzyme Inhib Med Chem. 2023. PMID: 36629421 Free PMC article.
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