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"High-throughput screening of catalytically active inclusion bodies using laboratory automation and Bayesian optimization".
Microb Cell Fact. 2024 Feb 24;23(1):67. doi: 10.1186/s12934-024-02319-y.
Microb Cell Fact. 2024.
PMID: 38402403
Free PMC article.
Why are different estimates of the effective reproductive number so different? A case study on COVID-19 in Germany.
Brockhaus EK, Wolffram D, Stadler T, Osthege M, Mitra T, Littek JM, Krymova E, Klesen AJ, Huisman JS, Heyder S, Helleckes LM, An der Heiden M, Funk S, Abbott S, Bracher J.
Brockhaus EK, et al. Among authors: helleckes lm.
PLoS Comput Biol. 2023 Nov 27;19(11):e1011653. doi: 10.1371/journal.pcbi.1011653. eCollection 2023 Nov.
PLoS Comput Biol. 2023.
PMID: 38011276
Free PMC article.
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From frozen cell bank to product assay: high-throughput strain characterisation for autonomous Design-Build-Test-Learn cycles.
Helleckes LM, Puchta D, Czech H, Morschett H, Geinitz B, Wiechert W, Oldiges M.
Helleckes LM, et al.
Microb Cell Fact. 2023 Jul 14;22(1):130. doi: 10.1186/s12934-023-02140-z.
Microb Cell Fact. 2023.
PMID: 37452397
Free PMC article.
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Machine learning in bioprocess development: from promise to practice.
Helleckes LM, Hemmerich J, Wiechert W, von Lieres E, Grünberger A.
Helleckes LM, et al.
Trends Biotechnol. 2023 Jun;41(6):817-835. doi: 10.1016/j.tibtech.2022.10.010. Epub 2022 Nov 28.
Trends Biotechnol. 2023.
PMID: 36456404
Review.
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Explore or exploit? A model-based screening strategy for PETase secretion by Corynebacterium glutamicum.
Helleckes LM, Müller C, Griesbach T, Waffenschmidt V, Moch M, Osthege M, Wiechert W, Oldiges M.
Helleckes LM, et al.
Biotechnol Bioeng. 2023 Jan;120(1):139-153. doi: 10.1002/bit.28261. Epub 2022 Nov 11.
Biotechnol Bioeng. 2023.
PMID: 36225165
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Accelerated strain construction and characterization of C. glutamicum protein secretion by laboratory automation.
Müller C, Bakkes PJ, Lenz P, Waffenschmidt V, Helleckes LM, Jaeger KE, Wiechert W, Knapp A, Freudl R, Oldiges M.
Müller C, et al. Among authors: helleckes lm.
Appl Microbiol Biotechnol. 2022 Jun;106(12):4481-4497. doi: 10.1007/s00253-022-12017-7. Epub 2022 Jun 27.
Appl Microbiol Biotechnol. 2022.
PMID: 35759036
Free PMC article.
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Bayesian calibration, process modeling and uncertainty quantification in biotechnology.
Helleckes LM, Osthege M, Wiechert W, von Lieres E, Oldiges M.
Helleckes LM, et al.
PLoS Comput Biol. 2022 Mar 7;18(3):e1009223. doi: 10.1371/journal.pcbi.1009223. eCollection 2022 Mar.
PLoS Comput Biol. 2022.
PMID: 35255090
Free PMC article.
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