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Remodeling of Stromal Immune Microenvironment by Urolithin A Improves Survival with Immune Checkpoint Blockade in Pancreatic Cancer.
Mehra S, Garrido VT, Dosch AR, Lamichhane P, Srinivasan S, Singh SP, Zhou Z, De Castro Silva I, Joshi C, Ban Y, Datta J, Gilboa E, Merchant NB, Nagathihalli NS. Mehra S, et al. Among authors: nagathihalli ns. Cancer Res Commun. 2023 Jul 12;3(7):1224-1236. doi: 10.1158/2767-9764.CRC-22-0329. eCollection 2023 Jul. Cancer Res Commun. 2023. PMID: 37448553 Free PMC article.
Tobacco Carcinogen-Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer.
Srinivasan S, Totiger T, Shi C, Castellanos J, Lamichhane P, Dosch AR, Messaggio F, Kashikar N, Honnenahally K, Ban Y, Merchant NB, VanSaun M, Nagathihalli NS. Srinivasan S, et al. Among authors: nagathihalli ns. Cancer Res. 2018 Nov 1;78(21):6146-6158. doi: 10.1158/0008-5472.CAN-18-0579. Epub 2018 Sep 19. Cancer Res. 2018. PMID: 30232221 Free PMC article.
Urolithin A, a Novel Natural Compound to Target PI3K/AKT/mTOR Pathway in Pancreatic Cancer.
Totiger TM, Srinivasan S, Jala VR, Lamichhane P, Dosch AR, Gaidarski AA 3rd, Joshi C, Rangappa S, Castellanos J, Vemula PK, Chen X, Kwon D, Kashikar N, VanSaun M, Merchant NB, Nagathihalli NS. Totiger TM, et al. Among authors: nagathihalli ns. Mol Cancer Ther. 2019 Feb;18(2):301-311. doi: 10.1158/1535-7163.MCT-18-0464. Epub 2018 Nov 7. Mol Cancer Ther. 2019. PMID: 30404927 Free PMC article.
Combined Blockade of MEK and CDK4/6 Pathways Induces Senescence to Improve Survival in Pancreatic Ductal Adenocarcinoma.
Willobee BA, Gaidarski AA, Dosch AR, Castellanos JA, Dai X, Mehra S, Messaggio F, Srinivasan S, VanSaun MN, Nagathihalli NS, Merchant NB. Willobee BA, et al. Among authors: nagathihalli ns. Mol Cancer Ther. 2021 Jul;20(7):1246-1256. doi: 10.1158/1535-7163.MCT-19-1043. Epub 2021 May 17. Mol Cancer Ther. 2021. PMID: 34001634 Free PMC article.
Interleukin-1 signaling in solid organ malignancies.
Dosch AR, Singh S, Nagathihalli NS, Datta J, Merchant NB. Dosch AR, et al. Among authors: nagathihalli ns. Biochim Biophys Acta Rev Cancer. 2022 Jan;1877(1):188670. doi: 10.1016/j.bbcan.2021.188670. Epub 2021 Dec 16. Biochim Biophys Acta Rev Cancer. 2022. PMID: 34923027 Review.
Distinct mechanisms of innate and adaptive immune regulation underlie poor oncologic outcomes associated with KRAS-TP53 co-alteration in pancreatic cancer.
Datta J, Bianchi A, De Castro Silva I, Deshpande NU, Cao LL, Mehra S, Singh S, Rafie C, Sun X, Chen X, Dai X, Colaprico A, Sharma P, Dosch AR, Pillai A, Hosein PJ, Nagathihalli NS, Komanduri KV, Wilson JM, Ban Y, Merchant NB. Datta J, et al. Among authors: nagathihalli ns. Oncogene. 2022 Jul;41(28):3640-3654. doi: 10.1038/s41388-022-02368-w. Epub 2022 Jun 14. Oncogene. 2022. PMID: 35701533
Combined MEK and STAT3 Inhibition Uncovers Stromal Plasticity by Enriching for Cancer-Associated Fibroblasts With Mesenchymal Stem Cell-Like Features to Overcome Immunotherapy Resistance in Pancreatic Cancer.
Datta J, Dai X, Bianchi A, De Castro Silva I, Mehra S, Garrido VT, Lamichhane P, Singh SP, Zhou Z, Dosch AR, Messaggio F, Ban Y, Umland O, Hosein PJ, Nagathihalli NS, Merchant NB. Datta J, et al. Among authors: nagathihalli ns. Gastroenterology. 2022 Dec;163(6):1593-1612. doi: 10.1053/j.gastro.2022.07.076. Epub 2022 Aug 7. Gastroenterology. 2022. PMID: 35948109 Free PMC article.
31 results