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Potent New Targets for Autophagy Enhancement to Delay Neuronal Ageing.
Cells. 2023 Jun 30;12(13):1753. doi: 10.3390/cells12131753.
Cells. 2023.
PMID: 37443788
Free PMC article.
The Small-Molecule Enhancers of Autophagy AUTEN-67 and -99 Delay Ageing in Drosophila Striated Muscle Cells.
Komlós M, Szinyákovics J, Falcsik G, Sigmond T, Jezsó B, Vellai T, Kovács T.
Komlós M, et al. Among authors: szinyakovics j.
Int J Mol Sci. 2023 Apr 30;24(9):8100. doi: 10.3390/ijms24098100.
Int J Mol Sci. 2023.
PMID: 37175806
Free PMC article.
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A conserved MTMR lipid phosphatase increasingly suppresses autophagy in brain neurons during aging.
Kovács T, Szinyákovics J, Billes V, Murányi G, Varga VB, Bjelik A, Légrádi Á, Szabó M, Sándor S, Kubinyi E, Szekeres-Paracky C, Szocsics P, Lőke J, Mulder J, Gulyás B, Renner É, Palkovits M, Gulya K, Maglóczky Z, Vellai T.
Kovács T, et al. Among authors: szinyakovics j.
Sci Rep. 2022 Dec 17;12(1):21817. doi: 10.1038/s41598-022-24843-w.
Sci Rep. 2022.
PMID: 36528685
Free PMC article.
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Autophagy is required for spermatogonial differentiation in the Drosophila testis.
Varga VB, Schuller D, Szikszai F, Szinyákovics J, Puska G, Vellai T, Kovács T.
Varga VB, et al. Among authors: szinyakovics j.
Biol Futur. 2022 Jun;73(2):187-204. doi: 10.1007/s42977-022-00122-7. Epub 2022 Jun 7.
Biol Futur. 2022.
PMID: 35672498
Review.
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The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms.
Kovács T, Billes V, Komlós M, Hotzi B, Manzéger A, Tarnóci A, Papp D, Szikszai F, Szinyákovics J, Rácz Á, Noszál B, Veszelka S, Walter FR, Deli MA, Hackler L Jr, Alfoldi R, Huzian O, Puskas LG, Liliom H, Tárnok K, Schlett K, Borsy A, Welker E, Kovács AL, Pádár Z, Erdős A, Legradi A, Bjelik A, Gulya K, Gulyás B, Vellai T.
Kovács T, et al. Among authors: szinyakovics j.
Sci Rep. 2017 Feb 16;7:42014. doi: 10.1038/srep42014.
Sci Rep. 2017.
PMID: 28205624
Free PMC article.
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